Research Outputs
(Articles)

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Overexpression of Trypanosoma cruzi High Mobility Group B protein (TcHMGB) alters the nuclear structure, impairs cytokinesis and reduces the parasite infectivity [2019]

Tavernelli, Luis Emilio; Motta, Maria Cristina M.; Gonçalves, Camila Silva; Silva, Marcelo Santos da ; Elias, Maria Carolina ; Alonso, Victoria Lucia; Serra, Esteban; Cribb, Pamela
Sci Rep 2019 Jan;9:192

DNA lesions that block transcription induce the death of Trypanosoma cruzi via ATR activation, which is dependent on the presence of R-loops [2024]

Mendes, Isabela Cecilia; Bertoldo, Willian dos Reis; Miranda-Junior, Adalberto Sales; Pavani, Raphael Souza; Elias, Maria Carolina
DNA Repair 2024 Jul; 141:103726

Deciphering divergent Trypanosomatid nuclear complexes by analyzing interactomic datasets with AlphaFold2 and genetic approaches [2023]

Araya, Elvio Rodriguez; Merli, Marcelo L.; Cribb, Pamela; Souza, Vinicius Carius de
ACS Infect Dis 2023 May; 9:1267–1282