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Results 1-20 of 28

Adjuvanted leptospiral vaccines: challenges and future development of new leptospirosis vaccines [2019]

Teixeira, Aline Rodrigues Florêncio ; Fernandes, Luis Guilherme Vírgílio ; Pereira, Maria Fernanda Cavenague ; Takahashi, Maria Beatriz ; Santos, Jademilson Celestino dos ; Passalia, Felipe José ; Daroz, Brenda ; Kochi, Leandro Toshio ; Vieira, Mônica Larucci ; Nascimento, Ana Lúcia Tabet Oller do
Vaccine 2019 July;37(30):3961-3973

Application of CRISPR interference (CRISPRi) for gene silencing in pathogenic species of Leptospira [2021]

Fernandes, L. G. V.; Hornsby, R. L.; Nascimento, Ana Lúcia Tabet Oller do ; Nally, J. E.
Genetics 2021 Aug;174:e62631

Binding of human plasminogen by the lipoprotein LipL46 of Leptospira interrogans [2018]

Santos, Jadson Viana ; Pereira, Priscila Romero Mazzini ; Fernandes, Luis Guilherme Vírgílio ; Siqueira, Gabriela Hase; Souza, Gisele O. de; Souza Filho, Antônio; Vasconcellos, Silvio A.; Heinemann, Marcos B.; Chapola, Erica G. B.; Nascimento, Ana Lúcia Tabet Oller do
Mol Cell Probes 2018 Feb;37:12-21

Characterization of a novel protein of Leptospira interrogans exhibiting plasminogen, vitronectin and complement binding properties [2019]

Pereira, Maria Fernanda Cavenague ; Teixeira, Aline Rodrigues Florêncio ; Filho, Antonio S.; Souza, Gisele O. de; Vasconcellos, Silvio A.; Heinemann, Marcos B.; Nascimento, Ana Lúcia Tabet Oller do
Int J Med Microbiol 2019 Mar;309(2):116-129

Chimeras could help in the fight against leptospirosis [2018]

Santos, Jademilson Celestino dos ; Nascimento, Ana Lúcia Tabet Oller do
eLife 2018 Jan;7:e34087

Evaluation of Lsa46 and Lsa77 leptospiral proteins for their immunoprotective activities in hamster model of leptospirosis [2018]

Teixeira, Aline Rodrigues Florêncio ; Fernandes, Luis Guilherme Vírgílio ; Souza Filho, Antônio; Souza, Gisele O. de; Vasconcellos, Silvio A.; Heinemann, Marcos B.; Nascimento, Ana Lúcia Tabet Oller do
Biomed Res Int 2018;2018:1813745

Gene silencing based on RNA-guided catalytically inactive Cas9 (dCas9): a new tool for genetic engineering in Leptospira [2019]

Fernandes, Luis Guilherme Vírgílio ; Guaman, L. P.; Vasconcellos, S. A.; Heinemann, Marcos B.; Picardeau, M.; Nascimento, Ana Lúcia Tabet Oller do
Sci Rep 2019 Feb;9:1839

Genetic manipulation of pathogenic Leptospira: CRISPR interference (CRISPRi)-mediated gene silencing and rapid mutant recovery at 37 °C [2021]

Fernandes, Luis Guilherme Vírgílio ; Hornsby, R. L.; Nascimento, Ana Lúcia Tabet Oller do ; Nally, J. E.
Commun Biol 2021 Jan;11:1768

Heparin-binding protein release is strongly induced by Leptospira species and is a candidate for an early diagnostic marker of human Leptospirosis [2019]

Vieira, Mônica Larucci ; Persson, Sandra; Lopes-Ferreira, Monica ; Romero, Eliete C.; Kirchgatter, Karin; Nascimento, Ana Lúcia Tabet Oller do ; Herwald, Heiko
J infect dis 2019 Mar;219(6):996-1006

Heterologous expression of the pathogen-specific LIC11711 gene in the Saprophyte L. biflexa increases bacterial binding to laminin and plasminogen [2020]

Kochi, Leandro Toshio ; Fernandes, Luis Guilherme Vírgílio ; Nascimento, Ana Lúcia Tabet Oller do
Pathogens 2020 Jul;9(8):599

Identification of a novel protein in the genome sequences of Leptospira interrogans with the ability to interact with host's components [2020]

Rossini, Amanda Diaz ; Teixeira, Aline Rodrigues Florêncio ; Souza Filho, A.; Souza, G.O.; Vasconcellos, S.A.; Heinemann, M.B.; Romero, E.C.; Nascimento, Ana Lúcia Tabet Oller do
J Microbiol Immunol Infect 2020 Feb;53(1):163-175

Identification of leptospiral protein antigens recognized by WC1+ γδ T cell subsets as target for development of recombinant vaccines [2021]

Teixeira, Aline Rodrigues Florêncio ; Gillespie, Alexandria; Yirsaw, Alehegne; Britton, Emily; Telfer, Janice C.; Nascimento, Ana Lúcia Tabet Oller do ; Baldwin, Cynthia L.
Infect. Immun. 2021 Oct;in press

Immunoprotective activity induced by leptospiral outer membrane proteins in hamster model of acute leptospirosis [2020]

Teixeira, Aline Rodrigues Florêncio ; Pereira, Maria Fernanda Cavenague ; Kochi, Leandro Toshio ; Fernandes, Luis Guilherme Vírgílio ; Souza, Gisele O; Souza Filho, Antonio Francisco de; Vasconcellos, Silvio A.; Heinemann, Marcos Bryan; Nascimento, Ana Lúcia Tabet Oller do
Front Immunol 2020 Oct;10:568694

In silico analysis of genetic VapC profiles from the toxin-antitoxin type II VapBC modules among pathogenic, intermediate, and non-pathogenic Leptospira [2019]

Lopes, Alexandre Paulo Yague ; Azevedo, Bruna Oliveira Pigatto ; Emídio, Rebeca Cordellini ; Damiano, Deborah Kohn ; Nascimento, Ana Lúcia Tabet Oller do ; Barazzone, Giovana Cappio
Microorganisms 2019 Feb;7(2):56

In silico structural and functional characterization of HtrA proteins of leptospira spp.: possible implications in pathogenesis [2020]

Daroz, Brenda ; Fernandes, Luis Guilherme Vírgílio ; Teixeira, Aline Rodrigues Florêncio ; Nascimento, Ana Lúcia Tabet Oller do
Trop Med Infect Dis 2020 Nov;5(4):179

Leptospira interrogans Bat proteins impair host hemostasis by fibrinogen cleavage and platelet aggregation inhibition [2020]

Passalia, Felipe José ; Heinemann, Marcos Bryan; Chudzinski, Sonia Aparecida de Andrade ; Nascimento, Ana Lúcia Tabet Oller do ; Vieira, Mônica Larucci
Med Microbiol Immunol 2020 Feb;209:201-213

Leptospira interrogans outer membrane protein LipL21 is a potent inhibitor of neutrophil myeloperoxidase [2018]

Vieira, Mônica Larucci ; Teixeira, Aline Rodrigues Florêncio ; Pidde-Queiroz, Giselle ; Ching, Ana Tung Ching ; Tambourgi, Denise Vilarinho ; Nascimento, Ana Lúcia Tabet Oller do ; Herwald, Heiko
Virulence 2018 Mar;9(1):414-25

A novel leptospira interrogans protein LIC13086 inhibits fibrin clot formation and Interacts with host components [2021]

Passalia, Felipe José; Heinemann, Marcos Bryan; Vieira, Mônica Larucci; Nascimento, Ana Lúcia Tabet Oller do
Front. Cell. Infect. Microbiol. 2021 July;11:708739

Proteomics as a tool to understand Leptospira physiology and virulence: recent advances, challenges and clinical implications [2018]

Filho, Edson Galdino do Nascimento ; Vieira, Mônica Larucci ; Teixeira, Aline Rodrigues Florêncio ; Santos, Jademilson Celestino dos ; Fernandes, Luis Guilherme Vírgílio ; Passalia, Felipe José ; Daroz, Brenda ; Rossini, Amanda Diaz ; Kochi, Leandro Toshio ; Pereira, Maria Fernanda Cavenague ; Pimenta, Daniel Carvalho ; Nascimento, Ana Lúcia Tabet Oller do
J Proteomics 2018 May;180:80-7

A review on host-leptospira interactions: what we know and future expectations [2021]

Daroz, Brenda; Fernandes, Luis Guilherme Vírgílio; Pereira, Maria Fernanda Cavenague; Kochi, Leandro Toshio; Passalia, Felipe José; Takahashi, Maria Beatriz; Filho, Edson Galdino do Nascimento; Teixeira, Aline Rodrigues Florêncio; Nascimento, Ana Lúcia Tabet Oller do
Front. Cell. Infect. Microbiol 2021 Nov;11:777709