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Results 1-20 of 44

Adjuvanted leptospiral vaccines: challenges and future development of new leptospirosis vaccines [2019]

Teixeira, Aline Rodrigues Florêncio ; Fernandes, Luis Guilherme Vírgílio ; Pereira, Maria Fernanda Cavenague ; Takahashi, Maria Beatriz ; Santos, Jademilson Celestino dos ; Passalia, Felipe José ; Daroz, Brenda ; Kochi, Leandro Toshio ; Vieira, Mônica Larucci ; Nascimento, Ana Lúcia Tabet Oller do
Vaccine 2019 July;37(30):3961-3973

Application of CRISPR interference (CRISPRi) for gene silencing in pathogenic species of Leptospira [2021]

Fernandes, Luis Guilherme Vírgílio ; Hornsby, R. L.; Nascimento, Ana Lúcia Tabet Oller do ; Nally, J. E.
JoVE 2021 Aug;174:e62631

Binding of human plasminogen by the lipoprotein LipL46 of Leptospira interrogans [2018]

Santos, Jadson Viana ; Pereira, Priscila Romero Mazzini ; Fernandes, Luis Guilherme Vírgílio ; Siqueira, Gabriela Hase; Souza, Gisele O. de; Souza Filho, Antônio; Vasconcellos, Silvio A.; Heinemann, Marcos B.; Chapola, Erica G. B.; Nascimento, Ana Lúcia Tabet Oller do
Mol Cell Probes 2018 Feb;37:12-21

Cell adhesion assay to study leptospiral proteins: an approach to investigate host-pathogen interaction [2020]

Teixeira, Aline Rodrigues Florêncio ; Nascimento, Ana Lúcia Tabet Oller
Book chapter 2020 Jul; 2134:15

Characterization of a novel protein of Leptospira interrogans exhibiting plasminogen, vitronectin and complement binding properties [2019]

Pereira, Maria Fernanda Cavenague ; Teixeira, Aline Rodrigues Florêncio ; Filho, Antonio S.; Souza, Gisele O. de; Vasconcellos, Silvio A.; Heinemann, Marcos B.; Nascimento, Ana Lúcia Tabet Oller do
Int J Med Microbiol 2019 Mar;309(2):116-129

Evaluation of Leptospira interrogans knockdown mutants for LipL32, LipL41, LipL21, and OmpL1 proteins [2023]

Fernandes, Luis Guilherme Vírgílio ; Teixeira, Aline Rodrigues Florêncio ; Nascimento, Ana Lúcia Tabet Oller
Front Microbiol 2023 Jun; 14:1199660

Evaluation of LipL32 and LigA/LigB knockdown mutants in Leptospira interrogans serovar copenhageni: impacts to proteome and virulence [2022]

Fernandes, Luis Guilherme Vírgílio ; Putz, Ellie J.; Stasko, Judith; Lippolis, John D.; Nascimento, Ana Lúcia Tabet Oller ; Nally, Jarlath E.
Front Microbiol 2022 Feb;12:799012

Evaluation of Lsa46 and Lsa77 leptospiral proteins for their immunoprotective activities in hamster model of leptospirosis [2018]

Teixeira, Aline Rodrigues Florêncio ; Fernandes, Luis Guilherme Vírgílio ; Souza Filho, Antônio; Souza, Gisele O. de; Vasconcellos, Silvio A.; Heinemann, Marcos B.; Nascimento, Ana Lúcia Tabet Oller do
Biomed Res Int 2018; 2018:1813745

Gene silencing based on RNA-guided catalytically inactive Cas9 (dCas9): a new tool for genetic engineering in Leptospira [2019]

Fernandes, Luis Guilherme Vírgílio ; Guaman, L. P.; Vasconcellos, S. A.; Heinemann, Marcos B.; Picardeau, M.; Nascimento, Ana Lúcia Tabet Oller do
Sci Rep 2019 Feb;9:1839

Genetic manipulation of pathogenic Leptospira: CRISPR interference (CRISPRi)-mediated gene silencing and rapid mutant recovery at 37 °C [2021]

Fernandes, Luis Guilherme Vírgílio ; Hornsby, R. L.; Nascimento, Ana Lúcia Tabet Oller do ; Nally, J. E.
Sci Rep 2021 Jan;11:1768

Global proteome of the saprophytic strain Leptospira biflexa and comparative analysis with pathogenic strain Leptospira interrogans uncover new pathogenesis mechanisms [2024]

Filho, Edson G. Nascimento; Vieira, Mônica L.; Dias, Meriellen; Mendes, Maria A.; Sanchez, Fabio B.; Setubal, João C.; Heinemann, Marcos B.; Souza, Gisele O.; Pimenta, Daniel Carvalho ; Nascimento, Ana Lúcia Tabet Oller
J Proteomics 2024 Apr; 297:105125

Heparin-binding protein release is strongly induced by Leptospira species and is a candidate for an early diagnostic marker of human Leptospirosis [2019]

Vieira, Mônica Larucci ; Persson, Sandra; Lopes-Ferreira, Monica ; Romero, Eliete C.; Kirchgatter, Karin; Nascimento, Ana Lúcia Tabet Oller do ; Herwald, Heiko
J infect dis 2019 Mar;219(6):996-1006

Heterologous expression of the pathogen-specific LIC11711 gene in the Saprophyte L. biflexa increases bacterial binding to laminin and plasminogen [2020]

Kochi, Leandro Toshio ; Fernandes, Luis Guilherme Vírgílio ; Nascimento, Ana Lúcia Tabet Oller do
Pathogens 2020 Jul;9(8):599

Host cell binding mediated by Leptospira interrogans adhesins [2022]

Takahashi, Maria Beatriz; Teixeira, Aline Rodrigues Florêncio ; Nascimento, Ana Lúcia Tabet Oller
Int J Mol Sci 2022 Oct-Dec; 23(24):15550

Identificação dos fatores de virulência da Leptospira interrogans através de análises proteômicas comparativas [2022]

Nascimento, Ana Lúcia Tabet Oller
Dataset

Identification of a novel protein in the genome sequences of Leptospira interrogans with the ability to interact with host's components [2020]

Rossini, Amanda Diaz ; Teixeira, Aline Rodrigues Florêncio ; Souza Filho, A.; Souza, G.O.; Vasconcellos, S.A.; Heinemann, M.B.; Romero, E.C.; Nascimento, Ana Lúcia Tabet Oller do
J Microbiol Immunol Infect 2020 Feb;53(1):163-175

Identification of leptospiral protein antigens recognized by WC1+ γδ T cell subsets as target for development of recombinant vaccines [2022]

Teixeira, Aline Rodrigues Florêncio ; Gillespie, Alexandria; Yirsaw, Alehegne; Britton, Emily; Telfer, Janice C.; Nascimento, Ana Lúcia Tabet Oller do ; Baldwin, Cynthia L.
Infect Immun 2022 Oct;90(1):e00492-21

Immunoprotective activity induced by leptospiral outer membrane proteins in hamster model of acute leptospirosis [2020]

Teixeira, Aline Rodrigues Florêncio ; Pereira, Maria Fernanda Cavenague ; Kochi, Leandro Toshio ; Fernandes, Luis Guilherme Vírgílio ; Souza, Gisele O; Souza Filho, Antonio Francisco de; Vasconcellos, Silvio A.; Heinemann, Marcos Bryan; Nascimento, Ana Lúcia Tabet Oller do
Front Immunol 2020 Oct;10:568694

In silico analysis and functional characterization of a leucine-rich repeat protein of leptospira interrogans [2024]

Inácio, Joao Pedro Gaspar ; Takahashi, Maria Beatriz ; Teixeira, Aline Rodrigues Florêncio ; Nascimento, Ana Lúcia Tabet Oller
Int J Med Microbiol 2024 Sep; 316:151633

In silico analysis of genetic VapC profiles from the toxin-antitoxin type II VapBC modules among pathogenic, intermediate, and non-pathogenic Leptospira [2019]

Lopes, Alexandre Paulo Yague ; Azevedo, Bruna Oliveira Pigatto ; Emídio, Rebeca Cordellini ; Damiano, Deborah Kohn ; Nascimento, Ana Lúcia Tabet Oller do ; Barazzone, Giovana Cappio
Microorganisms 2019 Feb;7(2):56