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Results 1-6 of 6

Aryl thiosemicarbazones for the treatment of trypanosomatidic infections [2018]

Linciano, Pasquale; Moraes, Carolina Borsoi ; Alcantara, Laura M.; Franco, Caio Haddad ; Pascoalino, Bruno; Freitas-Junior, Lucio Holanda Gondim ; Macedo, Sara; Santarem, Nuno; Cordeiro-da-Silva, Anabela; Gul, Sheraz; Witt, Gesa; Kuzikov, Maria; Ellinger, Bernhard; Ferrari, Stefania; Luciani, Rosaria; Quotadamo, Antonio; Costantino, Luca; Costi, Maria Paola
Eur J Med Chem 2018 Feb;146:423-34

Development of a focused library of triazole-linked privileged-structure-based conjugates leading to the discovery of novel phenotypic hits against protozoan parasitic infections [2018]

Uliassi, Elisa; Piazzi, Lorna; Mazzanti, Andrea; Kaiser, Marcel; Brun, Reto; Moraes, Carolina Borsoi ; Freitas-Junior, Lucio Holanda Gondim ; Gul, Sheraz; Kuzikov, Maria; Ellinger, Bernhard; Borsari, Chiara; Costi, Maria Paola; Bolognesi, Maria Laura; Belluti, Federica
ChemMedChem 2018 Apr;13(7):678-83

Expanding the biological application of fluorescent benzothiadiazole derivatives: a phenotypic screening strategy for anthelmintic drug discovery using caenorhabditis elegans [2019]

Cintra, Giovana Aparecida de Souza ; Neto, Brenno A. D.; Carvalho, Pedro H. P. R.; Moraes, Carolina Borsoi ; Freitas-Junior, Lucio Holanda Gondim
SLAS Discov 2019 June;24(7):755-765

Identification of di-substituted ureas that prevent growth of trypanosomes through inhibition of translation initiation [2018]

Machado, Fabricio Castro; Franco, Caio Haddad ; dos Santos Neto, Jose Vitorino; Dias-Teixeira, Karina Luiza; Moraes, Carolina Borsoi ; Lopes, Ulisses Gazos; Aktas, Bertal Huseyin; Schenkman, Sergio
Sci Rep 2018 Mar;8:4857

Investigating the structure-activity relationships of N '-[(5-nitrofuran-2-yl) methylene] substituted hydrazides against Trypanosoma cruzi to design novel active compounds [2018]

Palace-Berl, Fanny; Pasqualoto, Kerly Fernanda Mesquita ; Zingales, Bianca; Moraes, Carolina Borsoi ; Bury, Mariana; Franco, Caio Haddad ; da Silva Neto, Adelson Lopes; Murayama, Joao Sussumu; Nunes, Solange Lessa; Silva, Marcelo Nunes; Tavares, Leoberto Costa
Eur J Med Chem 2018 Jan;144:29-40

A multi-species phenotypic screening assay for leishmaniasis drug discovery shows that active compounds display a high degree of species-specificity [2020]

Alcantara, Laura M.; Ferreira, Thalita Camêlo da Silva ; Fontana, Vanessa; Chatelain, Eric; Moraes, Carolina Borsoi ; Freitas-Junior, Lucio Holanda Gondim
Molecules 2020 May;25(11):2551