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Results 1-20 of 21

Action of copper(II) complex with ß-diketone and 1,10-phenanthroline (CBP-01) on sarcoma cells and biological effects under cell death [2019]

Polloni, Lorena; Silva, Ana Carolina de Seni; Teixeira, Samuel Cota; Azevedo, Fernanda Van Petten de Vasconcelos; Zóia, Mariana Alves Pereira; Silva, Marcelo Santos da ; Lima, Paula Marynella Alves Pereira; Correia, Lucas Ian Veloso; Almeida, Janaina do Couto; Silva, Cláudio Vieira da; Ávila, Veridiana de Melo Rodrigues; Goulart, Luiz Ricardo Filho; Morelli, Sandra; Guerra, Wendell; Oliveira Júnior, Robson José de
Biomed Pharmacother 2019 Jan;112:108586

Analysis of DNA Exchange Using Thymidine Analogs (ADExTA) in Trypanosoma cruzi [2018]

Silva, Marcelo Santos da ; Marin, Paula Andrea ; Elias, Maria Carolina ; Repolês, Bruno M.; Machado, Carlos R.
Bio Protoc 2018 Dec;8(24):e3125

ATR kinase is a crucial player mediating the DNA damage response in Trypanosoma brucei [2020]

Marin, Paula Andrea ; Gomez, Ricardo Obonaga ; Pavani, Raphael Souza ; Silva, Marcelo Santos da ; de Araujo, Christiane Bezerra ; Lima, André Arruda ; Avila, Carla Cristi Del Campo ; Cestari, Igor; Machado, Carlos Renato; Elias, Maria Carolina
Front Cell Dev Biol 2020 Dec;8:602956

Comparative analysis of the minimum number of replication origins in trypanosomatids and yeasts [2020]

Silva, Marcelo Santos da ; Vitarelli, Marcela de Oliveira ; Souza, Bruno Ferreira de ; Elias, Maria Carolina
Genes 2020 May;11(5):523

Cytotoxic and genotoxic effects on human keratinocytes triggered by sphingomyelinase D from Loxosceles venom [2020]

Silva, Marcelo Santos da ; Lopes, Priscila Hess ; Elias, Maria Carolina ; Tambourgi, Denise Vilarinho
Arch Toxicol 2020 jun;94:3563-3577

DNA topoisomerase 3α is involved in homologous recombination repair and replication stress response in Trypanosoma cruzi [2021]

Costa-Silva, Héllida Marina; Resende, Bruno Carvalho; Umaki, Adriana Castilhos Souza; Prado, Willian; Silva, Marcelo Santos da ; Virgílio, Stela; Macedo, Andrea Mara; Pena, Sérgio Danilo Junho; Tahara, Erich Birelli; Tosi, Luiz Ricardo Orsini; Elias, Maria Carolina ; Andrade, Luciana Oliveira; Reis-Cunha, João Luís; Franco, Glória Regina; Fragoso, Stenio Perdigão; Machado, Carlos Renato
Front. Cell Dev. Biol. 2021 May;9:633195w

Dual cellular localization of the Leishmania amazonensis Rbp38 (LaRbp38) explains its affinity for telomeric and mitochondrial DNA [2019]

Fernandes, Carlos A. H.; Perez, Arina M.; Barros, Andrea C.; Dreyer, Thiago R.; Morea, Edna Gicela O.; Fontes, Marcos R.M.; Cano, Maria Isabel N.; Silva, Marcelo Santos da
Biochimie 2019 Jul;162,15-25

Estimation of the minimum number of replication origins per chromosome in any organism [2020]

Silva, Marcelo Santos da
Bio Protoc 2020 Oct;10(20):e3798

Evaluation of mechanisms that may generate DNA lesions triggering antigenic variation in African trypanosomes [2018]

Silva, Marcelo Santos da ; Hovel-Miner, Galadriel A.; Briggs, Emma; Elias, Maria Carolina ; McCulloch, Richard D.
PLoS Pathog 2018;14(11):e1007321

Experimental evidences that P21 protein controls Trypanosoma cruzi replication and modulates the pathogenesis of infection [2019]

Teixeira, Thaise L.; Castilhos, Patrícia; Rodrigues, Cassiano C.; Silva, Aline A. da; Brígido, Rebecca TS.; Teixeira, Samuel C.; Borges, Bruna C.; Santos, Marlus A. Dos; Martins, Flávia A.; Santos, Paulo César F.; Servato, João Paulo S.; Silva, Marcelo Santos da ; Silva, M.J.B. da; Elias, Maria Carolina ; Silva, Claudio V. da
Microb pathog 2019 Oct;135:103618

Fibroblast growth factor 2 lethally sensitizes cancer cells to stress-targeted therapeutic inhibitors [2019]

Dias, Matheus Henrique ; Fonseca, Cecília Sella ; Zeidler, Julianna Dias ; Costa, Layra Lucy Maria Albuquerque da ; Silva, Marcelo Santos da ; Lopes, Eduardo Cararo ; Reis, Marcelo da Silva ; Noel, Vincent Olivier Jean-Marie ; Santos, Edmilson Ozorio dos ; Prior, Ian A.; Armelin, Hugo Aguirre
Mol Oncol 2019 Dec;13(2):290-306

A Fluorinated phenylbenzothiazole arrests the trypanosoma cruzi cell cycle and diminishes the Infection of mammalian host cells [2020]

Cuevas-Hernández, Roberto I.; Girard, Richard M. B. M.; Martínez-Cerón, Sarai; Silva, Marcelo Santos da ; Elias, Maria Carolina ; Crispim, Marcell; Trujillo-Ferrara, José G.; Silber, Ariel Mariano
Antimicrob Agents Chemother 2020 Feb;64(2):e01742-19

Genotoxic effects of BnSP-6, a Lys-49 phospholipase A2 (PLA2) homologue from Bothrops pauloensis snake venom, on MDA-MB-231 breast cancer cells [2018]

Silva, Makswell Ferreira S.; Lopes, Daiana Silva; Teixeira, Samuel Cota; Gimenes, Sarah Natalie Cirilo ; Azevedo, Fernanda Van Petten Vasconcelos; Polloni, Lorena; Borges, Bruna Cristina; Silva, Marcelo Santos da ; Barbosa, Marcelo José; Oliveira Júnior, Robson José de; Elias, Maria Carolina ; Da Silva, Cláudio Vieira; Yoneyama, Kelly Aparecida Geraldo; Rodrigues, Veridiana De Melo; Rodrigues, Renata Santos
Int J Biol Macromol 2018 Oct;118(part A):311-9

Increased ROS generation causes apoptosis-like death: mechanistic insights into the anti-Leishmania activity of a potent ruthenium(II) complex [2019]

Costa, Mônica Soares; Gonçalves, Yasmim Garcia; Teixeira, Samuel Cota; Nunes, Débora Cristina de Oliveira; Lopes, Daiana Silva; Silva, Cláudio Vieira da; Silva, Marcelo Santos da ; Borges, Bruna Cristina; Silva, Marcelo José Barbosa; Rodrigues, Renata Santos; Rodrigues, Veridiana De Melo; Von Poelhsitz, Gustavo; Yoneyama, Kelly Aparecida Geraldo
J Inorg Biochem 2019 Jun;44:111-120

Ortholog of the polymerase theta helicase domain modulates DNA replication in Trypanosoma cruzi [2019]

Lima, Loyze Paola Oliveira de ; Calderano, Simone Guedes ; Silva, Marcelo Santos da ; de Araujo, Christiane Bezerra ; Vasconcelos, Elton José Rosas de ; Iwai, Leo Kei ; Pereira, Cláudio A.; Fragoso, Stenio P.; Elias, Maria Carolina
Sci Rep 2019 Feb;9:2888

Overexpression of Trypanosoma cruzi High Mobility Group B protein (TcHMGB) alters the nuclear structure, impairs cytokinesis and reduces the parasite infectivity [2019]

Tavernelli, Luis Emilio; Motta, Maria Cristina M.; Gonçalves, Camila Silva; Silva, Marcelo Santos da ; Elias, Maria Carolina ; Alonso, Victoria Lucia; Serra, Esteban; Cribb, Pamela
Sci Rep 2019 Jan;9:192

Pentachloropseudilin impairs angiogenesis by disrupting the actin cytoskeleton, integrin trafficking and the cell cycle [2019]

Teixeira, Samuel Cota; Lopes, Daiana Silva; Silva, Marcelo Santos da ; Luz, Felipe Andrés Cordero da; Gimenes, Sarah Natalie Cirilo ; Borges, Bruna Cristina; Silva, Aline Alves da; Martins, Flávia Alves; Santos, Marlus Alves dos; Teixeira, Thaise Lara; Oliveira, Ricardo A.; Ávila, Veridiana de Melo Rodrigues; Silva, Marcelo José Barbosa; Elias, Maria Carolina ; Martin, René; Silva, Claudio Vieira da; Knölker, Hans‐Joachim
Chembiochem 2019 Sept;20(18):2390-2401

Recruitment kinetics of the homologous recombination pathway in procyclic forms of Trypanosoma brucei after ionizing radiation treatment [2018]

Marin, Paula Andrea ; Silva, Marcelo Santos da ; Pavani, Raphael Souza ; Machado, Carlos Renato; Elias, Maria Carolina
Sci Rep 2018 Mar;8:5405

The recombinase Rad51 plays a key role in events of genetic exchange in Trypanosoma cruzi [2018]

Alves, Ceres Luciana; Repolês, Bruno Marcal; Silva, Marcelo Santos da ; Mendes, Isabela Cecília; Marin, Paula Andrea ; Aguiar, Pedro Henrique Nascimento; Santos, Selma da Silva; Franco, Glória Regina; Macedo, Andréa Mara; Pena, Sérgio Danilo Junho; Andrade, Luciana de Oliveira; Guarneri, Alessandra Aparecida; Tahara, Erich Birelli; Elias, Maria Carolina ; Machado, Carlos Renato
Sci Rep 2018;8:13335

Transcription activity contributes to the firing of non-constitutive origins in African trypanosomes helping to maintain robustness in S-phase duration [2019]

Silva, Marcelo Santos da ; Cayres-Silva, Gustavo Rodrigues ; Vitarelli, Marcela de Oliveira ; Marin, Paula Andrea ; Hiraiwa, Priscila M.; de Araujo, Christiane Bezerra ; Scholl, Bruno Boaventura ; Ávila, Andrea R.; McCulloch, Richard D.; Reis, Marcelo da Silva ; Elias, Maria Carolina
Sci rep 2019 Dec;9:18512