Insights on zika virus envelope gene conservation in american outbreaks

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dc.contributorLaboratório de Parasitologiapt_BR
dc.contributor.authorThomazella, Mateus V.pt_BR
dc.contributor.authorLima Neto, Quirino A.pt_BR
dc.contributor.authorDuarte Junior, Francisco F.pt_BR
dc.contributor.authorJorge, Fernando A.pt_BR
dc.contributor.authorMoreira, Déborah de Castropt_BR
dc.contributor.authorLeal Junior, Amauri D.pt_BR
dc.contributor.authorPresibella, Mayra M.pt_BR
dc.contributor.authorRiediger, Irina N.pt_BR
dc.contributor.authorSilva, Rafael Alves dapt_BR
dc.contributor.authorMello, Isabel Maria Vicente Guedes de Carvalhopt_BR
dc.contributor.authorBertolini, Dennis A.pt_BR
dc.date.accessioned2020-08-12T14:28:39Z-
dc.date.available2020-08-12T14:28:39Z-
dc.date.issued2020-
dc.identifier.citationThomazella MV., Lima Neto QA., Duarte Junior FF., Jorge FA., Moreira DC, Leal Junior AD., et al. Insights on zika virus envelope gene conservation in american outbreaks. Braz. J. Microbiol.. 2020 Aug. doi:10.1007/s42770-020-00349-3.pt_BR
dc.identifier.issn1517-8382-
dc.identifier.issn1678-4405-
dc.identifier.urihttps://repositorio.butantan.gov.br/handle/butantan/3127-
dc.description.abstractPhylogenetic studies with Zika virus (ZIKV) have been conducted in Brazil. In this study, we sequenced 8 new sequences of the ZIKV envelope (E) gene from strains of cases from the Paraná and Mato Grosso do Sul states in 2016. A low phylogenetic signal was observed, with more than 40% of unresolved quartets, and the Maximum Likelihood Tree grouped all sequences in the Brazilian branches within the Asian genotype. In addition, a Shannon entropy analysis was conducted, showing a high stability in the E protein through the ZIKV polyprotein. Taken together, these results suggest a high degree of conservation in the ZIKV E gene from the recent American outbreaks.pt_BR
dc.description.sponsorshipFundação Araucária de Apoio ao Desenvolvimento Científico e Tecnológico do Estado do Paraná (FA)pt_BR
dc.languageengpt_BR
dc.publisherSpringer International Publishingpt_BR
dc.relation.ispartofBrazilian Journal of Microbiologypt_BR
dc.titleInsights on zika virus envelope gene conservation in american outbreakspt_BR
dc.typeArticlept_BR
dc.identifier.doi10.1007/s42770-020-00349-3pt_BR
dc.identifier.urlhttps://doi.org/10.1007/s42770-020-00349-3pt_BR
dc.contributor.externalUniversidade Estadual de Maringá (UEM)pt_BR
dc.contributor.externalLaboratório Central do Estado do Paraná (LACEN)pt_BR
dc.contributor.externalUniversidade Federal de São Paulo (UNIFESP)pt_BR
dc.subject.keywordZika viruspt_BR
dc.subject.keywordPhylogenetic studypt_BR
dc.subject.keywordEntropypt_BR
dc.subject.keywordBrazilpt_BR
dc.relation.ispartofabbreviatedBraz. J. Microbiol.pt_BR
dc.identifier.citationabntago. 2020pt_BR
dc.identifier.citationvancouver2020 Augpt_BR
dc.publisher.countrySwitzerlandpt_BR
dc.contributor.butantanda Silva, Rafael Alves|:Aluno|:Laboratório de Parasitologiapt_BR
dc.contributor.butantanMello, Isabel Maria Vicente Guedes de Carvalho|:Pesquisador|:Laboratório de Parasitologiapt_BR
dc.sponsorship.butantanFundação Araucária de Apoio ao Desenvolvimento Científico e Tecnológico do Estado do Paraná (FA)¦¦040/2016pt_BR
dc.identifier.bvsccBR78.1pt_BR
dc.identifier.bvsdbIBProdpt_BR
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