What's in a mass?

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dc.contributorLab. Herpetologiapt_BR
dc.contributor.authorCalvete, Juan J.pt_BR
dc.contributor.authorSanz, Libiapt_BR
dc.contributor.authorMora-Obando, Dianapt_BR
dc.contributor.authorLomonte, Brunopt_BR
dc.contributor.authorTanaka-Azevedo, Anita Miticopt_BR
dc.contributor.authorMorais-Zani, Karen dept_BR
dc.contributor.authorSant'Anna, Sávio Stefaninipt_BR
dc.contributor.authorCaldeira, Cleópatra A.S.pt_BR
dc.date.accessioned2021-05-04T14:12:09Z-
dc.date.available2021-05-04T14:12:09Z-
dc.date.issued2021pt_BR
dc.identifier.citationCalvete JJ., Sanz L, Mora-Obando D, Lomonte B, Tanaka-Azevedo AM, Morais-Zani K, et al. What's in a mass?. Biochem Soc Trans. 2021 Apr;49(2):1027-1037. doi:10.1042/BST20210288.pt_BR
dc.identifier.urihttps://repositorio.butantan.gov.br/handle/butantan/3692-
dc.description.abstractThis short essay pretends to make the reader reflect on the concept of biological mass and on the added value that the determination of this molecular property of a protein brings to the interpretation of evolutionary and translational snake venomics research. Starting from the premise that the amino acid sequence is the most distinctive primary molecular characteristics of any protein, the thesis underlying the first part of this essay is that the isotopic distribution of a protein's molecular mass serves to unambiguously differentiate it from any other of an organism's proteome. In the second part of the essay, we discuss examples of collaborative projects among our laboratories, where mass profiling of snake venom PLA2 across conspecific populations played a key role revealing dispersal routes that determined the current phylogeographic pattern of the species.pt_BR
dc.description.sponsorshipMinisterio de Ciencia, Innovación y Universidadespt_BR
dc.format.extent1027-1037pt_BR
dc.language.isoEnglishpt_BR
dc.relation.ispartofBiochemical Society Transactionspt_BR
dc.rightsRestricted Accesspt_BR
dc.titleWhat's in a mass?pt_BR
dc.typeArticlept_BR
dc.identifier.doi10.1042/BST20210288pt_BR
dc.identifier.urlhttps://doi.org/10.1042/BST20210288pt_BR
dc.contributor.externalConsejo Superior de Investigaciones Cientificas (CSIC)pt_BR
dc.contributor.externalUniversidad de Costa Rica (UCR)pt_BR
dc.contributor.externalFundação Oswaldo Cruz (Fiocruz)pt_BR
dc.identifier.citationvolume49pt_BR
dc.identifier.citationissue2pt_BR
dc.subject.keywordbiological mass spectrometrypt_BR
dc.subject.keywordsnake venompt_BR
dc.subject.keywordvenomicspt_BR
dc.relation.ispartofabbreviatedBiochem Soc Transpt_BR
dc.identifier.citationabntv. 49, n. 2, p. 1027-1037, abr. 2021pt_BR
dc.identifier.citationvancouver2021 Apr;49(2):1027-1037pt_BR
dc.contributor.butantanTanaka-Azevedo, Anita Mitico|:Pesquisador|:Lab. Herpetologiapt_BR
dc.contributor.butantanMorais-Zani, Karen de|:Pesquisador|:Lab. Herpetologiapt_BR
dc.contributor.butantanSant'anna, Sávio Stefanini|:Pesquisador|:Lab. Herpetologiapt_BR
dc.sponsorship.butantanMinisterio de Ciencia, Innovación y Universidades¦¦BFU2017-89103-Ppt_BR
dc.identifier.bvsccBR78.1pt_BR
dc.identifier.bvsdbIBProdpt_BR
dc.description.dbindexedYespt_BR
item.grantfulltextembargo_29990101-
item.languageiso639-1English-
item.openairetypeArticle-
item.fulltextCom Texto completo-
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