Compound for modulating rlr, tlr, oas and/or oncostatin m pathways, use thereof for preparing a medicine, composition, method for modulating said pathways and method of treatment
Inventor
Butantan affiliation
Publication type
Patent
Language
English
Access rights
Open access
Appears in Collections:
Abstract
The invention falls within the fields of pharmaceutical sciences, immunology and methods of treatment of cancer Methods. More specifically, the invention relates to a compound for modulating one or more innate immune pathways selected from RLR, TLR, OAS and/or oncostatin M, said compound being amblyomin-X or peptides derived from amblyomin-X. Use of said compound for preparing medicines; a pharmaceutical composition comprising said compound, a method for modulating said pathways in vitro and a method of treatment are also described.
Abstract in Portuguese
A invenção se enquadra nos campos das ciências farmacêuticas, imunologia e métodos de tratamento do câncer. Mais especificamente, a invenção refere-se a um composto para modular uma ou mais vias imunes inatas selecionadas de RLR, TLR, OAS e/ou oncostatina M, sendo o referido composto ambliomina-X ou peptídeos derivados de ambliomina-X. Utilização do referido composto para a preparação de medicamentos; uma composição farmacêutica compreendendo o referido composto, um método para modular as vias in vitro e um método de tratamento também são descritos.
Patent Number
BR102018074043A2; EP3939995A1; WO2020102875A1
IPC Number
C07K14/81; C07K14/435; C07K7/06; C07K7/08; A61K38/57; A61K38/17; A61K38/08; A61K38/10; A61P35/00
Deposit Priority NUmber
BR102018074043A; BR2019050502W
metadata.dc.identifier.submitnumber
EP19887425A
Link to cite this reference
https://repositorio.butantan.gov.br/handle/butantan/4323
URL
https://worldwide.espacenet.com/patent/search/family/170773031/publication/EP3939995A1?q=EP3939995A1
Issue Date
2022
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