Nanog, Stat-3, and Sox-5 involvement in human fetal temporomandibular joint late development
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The temporomandibular joint (TMJ) is a synovial joint that allows the complex movements essential for life. It connects the jawbone to the skull, working as a sliding hinge. Moreover, pluripotent stem cells are a source of precursors and tissue-specific cells in developing organisms, however, their biodistribution in developing fetal tissues is weakly studied. The aim of our study was analyse immunohistochemical expression of Nanog, Oct-4, Sox-2 and Stat-3 and Sox-5, in TMJ tissue samples from human fetuses aged between the 12th and 20th weeks of intrauterine life.
Pagni TC, Cunha JM, Saez DM, Costa-Neves A, Kerkis I, Silva MCP. Nanog, Stat-3, and Sox-5 involvement in human fetal temporomandibular joint late development. Journal of Oral Biology and Craniofacial Research. 2023 Oct; 13(1):636-641. doi:10.1016/j.jobcr.2023.08.002.
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