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Results 1-7 of 7

A multi-species phenotypic screening assay for leishmaniasis drug discovery shows that active compounds display a high degree of species-specificity [2020]

Alcantara, Laura M.; Ferreira, Thalita Camêlo da Silva ; Fontana, Vanessa; Chatelain, Eric; Moraes, Carolina Borsoi ; Freitas-Junior, Lucio Holanda Gondim
Molecules 2020 May;25(11):2551

Leptospira interrogans secreted proteases degrade extracellular matrix and plasma proteins from the host [2018]

Silva, Ludmila Bezerra da ; Menezes, Milene Cristina ; Kitano, Eduardo Shigueo ; Oliveira, Ana K.; Abreu, Afonso G.; Souza, Gisele O. de; Heinemann, Marcos B.; Isaac, Lourdes; Fraga, Tatiana R.; Serrano, Solange Maria de Toledo ; Barbosa, Angela Silva
Front Cell Infect Microbiol 2018 Mar;8:92

Investigating the structure-activity relationships of N '-[(5-nitrofuran-2-yl) methylene] substituted hydrazides against Trypanosoma cruzi to design novel active compounds [2018]

Palace-Berl, Fanny; Pasqualoto, Kerly Fernanda Mesquita ; Zingales, Bianca; Moraes, Carolina Borsoi ; Bury, Mariana; Franco, Caio Haddad ; da Silva Neto, Adelson Lopes; Murayama, Joao Sussumu; Nunes, Solange Lessa; Silva, Marcelo Nunes; Tavares, Leoberto Costa
Eur J Med Chem 2018 Jan;144:29-40

Discordant congenital Zika syndrome twins show differential in vitro viral susceptibility of neural progenitor cells [2018]

Caires-Júnior, Luiz Carlos; Goulart, Ernesto; Melo, Uirá Souto; Schanoski, Alessandra Soares ; Amaral, Murilo Sena ; Astray, Renato Mancini ; Suarez-Patino, Sandra Fernanda ; Ventini, Daniella Cristina ; Verjovski-Almeida, Sergio ; Ho, Paulo Lee
Nat Commun 2018 Feb; 9:1114

Development of a focused library of triazole-linked privileged-structure-based conjugates leading to the discovery of novel phenotypic hits against protozoan parasitic infections [2018]

Uliassi, Elisa; Piazzi, Lorna; Mazzanti, Andrea; Kaiser, Marcel; Brun, Reto; Moraes, Carolina Borsoi ; Freitas-Junior, Lucio Holanda Gondim ; Gul, Sheraz; Kuzikov, Maria; Ellinger, Bernhard; Borsari, Chiara; Costi, Maria Paola; Bolognesi, Maria Laura; Belluti, Federica
ChemMedChem 2018 Apr;13(7):678-83

Cleavage of proteoglycans, plasma proteins and the platelet-derived growth factor receptor in the hemorrhagic process induced by snake venom metalloproteinases [2020]

Asega, Amanda Francine ; Menezes, Milene Cristina ; Silva, Dilza Trevisan ; Cajado-Carvalho, Daniela ; Nasciben, Luciana Bertholim ; Oliveira, Ana Karina de ; Zelanis, André; Serrano, Solange Maria de Toledo
Sci Rep 2020 Jul;10:12912

Aryl thiosemicarbazones for the treatment of trypanosomatidic infections [2018]

Linciano, Pasquale; Moraes, Carolina Borsoi ; Alcantara, Laura M.; Franco, Caio Haddad ; Pascoalino, Bruno; Freitas-Junior, Lucio Holanda Gondim ; Macedo, Sara; Santarem, Nuno; Cordeiro-da-Silva, Anabela; Gul, Sheraz; Witt, Gesa; Kuzikov, Maria; Ellinger, Bernhard; Ferrari, Stefania; Luciani, Rosaria; Quotadamo, Antonio; Costantino, Luca; Costi, Maria Paola
Eur J Med Chem 2018 Feb;146:423-34