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Results 1-20 of 30

Adjuvanted leptospiral vaccines: challenges and future development of new leptospirosis vaccines [2019]

Teixeira, Aline Rodrigues Florêncio ; Fernandes, Luis Guilherme Vírgílio ; Pereira, Maria Fernanda Cavenague ; Takahashi, Maria Beatriz ; Santos, Jademilson Celestino dos ; Passalia, Felipe José ; Daroz, Brenda ; Kochi, Leandro Toshio ; Vieira, Mônica Larucci ; Nascimento, Ana Lúcia Tabet Oller do
Vaccine 2019 July;37(30):3961-3973

Application of CRISPR interference (CRISPRi) for gene silencing in pathogenic species of Leptospira [2021]

Fernandes, Luis Guilherme Vírgílio ; Hornsby, R. L.; Nascimento, Ana Lúcia Tabet Oller do ; Nally, J. E.
JoVE 2021 Aug;174:e62631

Binding of human plasminogen by the lipoprotein LipL46 of Leptospira interrogans [2018]

Santos, Jadson Viana ; Pereira, Priscila Romero Mazzini ; Fernandes, Luis Guilherme Vírgílio ; Siqueira, Gabriela Hase; Souza, Gisele O. de; Souza Filho, Antônio; Vasconcellos, Silvio A.; Heinemann, Marcos B.; Chapola, Erica G. B.; Nascimento, Ana Lúcia Tabet Oller do
Mol Cell Probes 2018 Feb;37:12-21

Circulating foamy macrophages in the golden syrian hamster (Mesocricetus auratus) model of Leptospirosis [2021]

Putz, Ellie J; Andreasen, Claire B; Stasko, Judith A; Fernandes, Luis Guilherme Vírgílio ; Palmer, Mitchell V; Rauh, Michael J; Nally, Jarlath E
J Comp Pathol 2021 Nov;189:98-109

Distinct transcriptional profiles of Leptospira borgpetersenii serovar Hardjo strains JB197 and HB203 cultured at different temperatures [2021]

Putz, Ellie J.; Sivasankaran, Sathesh K.; Fernandes, Luis Guilherme Vírgílio ; Brunelle, Brian; Lippolis, John D.; Alt, David P.; Bayles, Darrell O.; Hornsby, Richard L.; Nally, Jarlath E.
Plos Negl Trop Dis 2021 Apr;15(4):e0009320

Diverse lineages of pathogenic Leptospira species are widespread in the environment in Puerto Rico, USA [2022]

Stone, Nathan E.; Hall, Carina M.; Ortiz, Marielisa; Fernandes, Luis Guilherme Vírgílio
PLoS Negl Trop Dis 2022 May; 16(5):e0009959

Evaluation of Leptospira interrogans knockdown mutants for LipL32, LipL41, LipL21, and OmpL1 proteins [2023]

Fernandes, Luis Guilherme Vírgílio ; Teixeira, Aline Rodrigues Florêncio ; Nascimento, Ana Lúcia Tabet Oller
Front Microbiol 2023 Jun; 14:1199660

Evaluation of LipL32 and LigA/LigB knockdown mutants in Leptospira interrogans serovar copenhageni: impacts to proteome and virulence [2022]

Fernandes, Luis Guilherme Vírgílio ; Putz, Ellie J.; Stasko, Judith; Lippolis, John D.; Nascimento, Ana Lúcia Tabet Oller ; Nally, Jarlath E.
Front Microbiol 2022 Feb;12:799012

Evaluation of Lsa46 and Lsa77 leptospiral proteins for their immunoprotective activities in hamster model of leptospirosis [2018]

Teixeira, Aline Rodrigues Florêncio ; Fernandes, Luis Guilherme Vírgílio ; Souza Filho, Antônio; Souza, Gisele O. de; Vasconcellos, Silvio A.; Heinemann, Marcos B.; Nascimento, Ana Lúcia Tabet Oller do
Biomed Res Int 2018; 2018:1813745

Gene silencing based on RNA-guided catalytically inactive Cas9 (dCas9): a new tool for genetic engineering in Leptospira [2019]

Fernandes, Luis Guilherme Vírgílio ; Guaman, L. P.; Vasconcellos, S. A.; Heinemann, Marcos B.; Picardeau, M.; Nascimento, Ana Lúcia Tabet Oller do
Sci Rep 2019 Feb;9:1839

Genetic manipulation of pathogenic Leptospira: CRISPR interference (CRISPRi)-mediated gene silencing and rapid mutant recovery at 37 °C [2021]

Fernandes, Luis Guilherme Vírgílio ; Hornsby, R. L.; Nascimento, Ana Lúcia Tabet Oller do ; Nally, J. E.
Sci Rep 2021 Jan;11:1768

Heterologous expression of the pathogen-specific LIC11711 gene in the Saprophyte L. biflexa increases bacterial binding to laminin and plasminogen [2020]

Kochi, Leandro Toshio ; Fernandes, Luis Guilherme Vírgílio ; Nascimento, Ana Lúcia Tabet Oller do
Pathogens 2020 Jul;9(8):599

Immunoprotective activity induced by leptospiral outer membrane proteins in hamster model of acute leptospirosis [2020]

Teixeira, Aline Rodrigues Florêncio ; Pereira, Maria Fernanda Cavenague ; Kochi, Leandro Toshio ; Fernandes, Luis Guilherme Vírgílio ; Souza, Gisele O; Souza Filho, Antonio Francisco de; Vasconcellos, Silvio A.; Heinemann, Marcos Bryan; Nascimento, Ana Lúcia Tabet Oller do
Front Immunol 2020 Oct;10:568694

In silico structural and functional characterization of HtrA proteins of leptospira spp.: possible implications in pathogenesis [2020]

Daroz, Brenda ; Fernandes, Luis Guilherme Vírgílio ; Teixeira, Aline Rodrigues Florêncio ; Nascimento, Ana Lúcia Tabet Oller do
Trop Med Infect Dis 2020 Nov;5(4):179

Leptospira sanjuanensis sp. nov., a pathogenic species of the genus Leptospira isolated from soil in Puerto Rico [2022]

Fernandes, Luis Guilherme Vírgílio ; Stone, Nathan E.; Roe, Chandler C.; Goris, Marga G. A.; Linden, Hans van der; Sahl, Jason W.; Wagner, David M.; Nally, Jarlath E.
Int J Syst Evol Microbiol 2022 Oct; 72(10):005560

Leptospira sanjuanensis sp. nov., a pathogenic species of the genus Leptospira isolated from soil in Puerto Rico [2022]

Fernandes, Luis Guilherme Vírgílio ; Stone, Nathan E.; Roe, Chandler C.; Goris, Marga G. A.; Linden, Hans van der; Sahl, Jason W.; Wagner, David M.; Nally, Jarlath E.
Int J Syst Evol Microbiol 2022 Oct; 72:005560

LIC12254 is a leptospiral protein that interacts with integrins via the RGD motif [2023]

Pereira, Maria Fernanda Cavenague; Teixeira, Aline Rodrigues Florêncio ; Fernandes, Luis Guilherme Vírgílio ; Nascimento, Ana Lúcia Tabet Oller
Trop Med and Infec Dis 2023 Apr; 8(5):249

LipL41 and LigA/LigB gene silencing on a LipL32 knockout Leptospira interrogans reveals the impact of multiple mutations on virulence [2023]

Fernandes, Luis Guilherme Vírgílio ; Foltran, Bruno Botega ; Teixeira, Aline Rodrigues Florêncio ; Nascimento, Ana Lúcia Tabet Oller
Pathogens 2023 Sep; 12(10):1191

Medical applications of clustered regularly interspaced short palindromic repeats (CRISPR/Cas) tool: a comprehensive overview [2020]

Araldi, Rodrigo Pinheiro; Khalil, Charbel; Grignet, Pedro Henrique; Teixeira, Michelli Ramires; Melo, Thatiana Correa de; Módolo, Diego Grando ; Fernandes, Luis Guilherme Vírgílio ; Ruiz, Jorge; Souza, Edislane Barreiros de
Gene 2020 Mar;745:144636

A modified ELISA method to evaluate the interaction of schistosoma mansoni proteins with plasminogen [2020]

Fernandes, Luis Guilherme Vírgílio ; Fernandes, Rafaela Sachetto; Nascimento, Ana Lúcia Tabet Oller ; Leite, Luciana Cezar de Cerqueira
Book chapter 2020 May; 2151:11