(CENTD) Centro de Excelência para Descoberta de Alvos Moleculares

Research Outputs
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Resultados encontrados

Results 21-40 of 52

Human sensory neuron-like cells and glycated collagen matrix as a model for the screening of analgesic compounds [2022]

Búfalo, Michelle Cristiane ; Almeida, Maíra Estanislau Soares de ; Jensen, José Ricardo ; De Ocesano-Pereira, Carlos ; Lichtenstein, Flavio ; Picolo, Gisele ; Chudzinski-Tavassi, Ana Marisa ; Sampaio, Sandra Coccuzzo ; Cury, Yara ; Zambelli, Vanessa Olzon
Cells 2022 Jan;11(2):247

Identification of purinergic system components in the venom of Bothrops mattogrossensis and the inhibitory effect of specioside extracted from Tabebuia aurea [2024]

Dias, Dhébora Albuquerque; Souza, Kamylla Fernanda Souza de; Moslaves, Iluska Senna Bonfá; Buri, Marcus Vinicius ; Chudzinski-Tavassi, Ana Marisa
Purinergic Signal 2024; in press

IL-1β and TNF-α modulation of proliferated and committed myoblasts: IL-6 and COX-2-derived prostaglandins as key actors in the mechanisms involved [2020]

Gómez, Angela María Alvarez ; De Ocesano-Pereira, Carlos ; Teixeira, Catarina de Fátima Pereira ; Moreira, Vanessa
Cells 2020 Sept;9(9):2005

Interaction of Graphene oxide particles and dendrimers with human breast cancer cells by real-time microscopy [2023]

Ribeiro, Beatriz Fumelli Monti; Chaves, Julyane Batista; Souza, Marcelo Medina de ; Keppler, Artur Franz; Carmo, Devaney Ribeiro Do; Machado-Santelli, Gláucia M.
Pharmaceutics 2023 Nov; 15(12)2655

A Kunitz-type inhibitor from tick salivary glands: a promising novel antitumor drug candidate [2022]

Lobba, Aline Ramos Maia ; Flores, Miryam Paola Alvarez ; Fessel, Melissa Regina ; Buri, Marcus Vinicius ; Oliveira, Douglas Souza ; Gomes, Renata Nascimento ; Cunegundes, Priscila Silva ; De Ocesano-Pereira, Carlos ; Cinel, Victor Dal Posolo; Chudzinski-Tavassi, Ana Marisa
Front Mol Biosci 2022 Aug; 9:936107

Lonomia obliqua envenoming and innovative research [2021]

Flores, Miryam Paola Alvarez ; Gomes, Renata Nascimento ; Trevisan Silva, Dilza ; Douglas Souza Oliveira; Batista, Isabel de Fátima Correia ; Buri, Marcus Vinicius ; Gómez, Angela María Alvarez ; De Ocesano-Pereira, Carlos ; Souza, Marcelo Medina de; Chudzinski-Tavassi, Ana Marisa
Toxins 2021 Nov; 13(12):832

Lonomia obliqua venom induces NF-κB activation and a pro-inflammatory profile in THP-1-derived macrophage [2021]

Oliveira, Douglas Souza; Souza, Jean Gabriel de ; Flores, Miryam Paola Alvarez ; Cunegundes, Priscila Silva ; De Ocesano-Pereira, Carlos ; Lobba, Aline Ramos Maia ; Gomes, Renata N.; Chudzinski-Tavassi, Ana Marisa
Toxins 2021 June;13(7):462

Losac and lopap recombinant proteins from Lonomia obliqua bristles positively modulate the myoblast proliferation process [2022]

Gómez, Angela María Alvarez ; Flores, Miryam Paola Alvarez ; De Ocesano-Pereira, Carlos ; Goldfeder, Mauricio Barbugiani ; Chudzinski-Tavassi, Ana Marisa ; Moreira, Vanessa; Teixeira, Catarina de Fátima Pereira
Front Mol Biosci 2022 June;9:904737

Meningitis caused by Aeromonas hydrophila in Oreochromis niloticus: proteomics and druggability of virulence factors [2024]

Fernandes, Dayanne Carla; Eto, Silas Fernandes ; Baldassi, Amanda Cristina; Balbuena, Thiago Santana; Charlie-Silva, Ives; Belo, Marco Antonio de Andrade; Pizauro, João Martins
Fish Shellfish Immunol 2024 Aug; 151:109687

A metalloproteinase induces an inflammatory response in preadipocytes with the activation of COX signalling pathways and participation of endogenous phospholipases A2 [2021]

Motta, Priscila Signor ; Leiguez, Elbio ; Portas, Viviane Barbosa ; Teixeira, Catarina de Fátima Pereira
Biomolecules 2021 June;11(7):921;

Novel cysteine protease inhibitor derived from the Haementeria vizottoi leech: recombinant expression, purification, and characterization [2021]

Linhares, Débora do Carmo; Faria, Fernanda ; Kodama, Roberto Tadashi; Amorim, Adriane Michele Xavier Prado ; Portaro, Fernanda Calheta Vieira ; Trevisan-Silva, Dilza; Ferraz, Karla Fernanda ; Chudzinski-Tavassi, Ana Marisa
Toxins 2021 Dec;13(12):857

A novel insight on SARS-CoV-2 S-derived fragments in the control of the host immunity [2023]

Bastos, Thais Sibioni Berti; de Paula, André Guilherme Portela; Luz, Rebeca Bosso dos Santos; Eto, Silas Fernandes ; Fernandes, Dayanne Carla
Sci Rep 2023 May; 13:8060

Pathophysiology of COVID-19: critical role of hemostasis [2022]

Chudzinski, Sonia Aparecida de Andrade ; Souza, Daniel Alexandre de; Torres, Amarylis Lins ; Lima, Cristiane Ferreira Graça de ; Ebram, Matteo Celano ; Celano, Rosa Maria Gaudioso; Schattner, Mirta; Chudzinski-Tavassi, Ana Marisa
Front Cell Infect Microbiol 2022 June;12:896972

PKC-α is involved in the signaling of phagocytosis induced by two snake venom secretory PLA2S in macrophages [2024]

Zuliani, Juliana Pavan ; Yamanouye, Norma ; Gutierrez, Jose Maria; Teixeira, Catarina de Fátima Pereira
Toxicon 2024 Jun; 247:107824

Plant Kunitz inhibitors and their Interaction with proteases: current and potential pharmacological targets [2022]

Bonturi, Camila Ramalho; Teixeira, Ana Beatriz Silva; Rocha, Vitória Morais; Valente, Penélope Ferreira; Oliveira, Juliana Rodrigues; Filho, Clovis Macêdo Bezerra; Batista, Isabel de Fátima Correia ; Oliva , Maria Luiza Vilela
Int J Mol Sci 2022 Apr; 23(9):4742

Processo de obtenção da proteína recombinante e uso da esculptina ou proteína recombinante para preparar um medicamento ou composição farmacêutica para profilaxia e/ou tratamento de doenças tromboembólicas ou como inibidor direto e específico da trombina [2018]

Chudzinski-Tavassi, Ana Marisa ; Goldfeder, Mauricio Barbugiani ; IQBAL, Asif
Patent CHUDZINSKI-TAVASSI, Ana Marisa GOLDFEDER; Mauricio Barbugiani; IQBAL, Asif; Fundação Butanseus fragtan. Proteína recombinante e mentos, processo de obtenção da proteína recombinante, gene sintético e uso da esculptina ou proteína recombinante para preparar um medicamento ou composição farmacêutica para profilaxia e/ou tratamento de doenças tromboembólicas ou como inibidor direto e específico da trombina. Patente. BR. WO/2018/170568. 27.09.2018

Proliferation and invasion of melanoma are suppressed by a plant protease inhibitor, leading to downregulation of survival/death-related proteins [2022]

Bonturi, Camila Ramalho; Salu, Bruno Ramos; Bonazza, Camila Nimri; Sinigaglia, Rita de Cassia; Rodrigues, Tiago; Flores, Miryam Paola Alvarez ; Chudzinski-Tavassi, Ana Marisa ; Oliva, Maria Luiza Vilela
Molecules 2022 May; 27(9):2956

Proteomic analysis identifies molecular players and biological processes specific to SARS-CoV-2 exposure in endothelial cells [2022]

Melo, Thatiana Correa de ; Trevisan Silva, Dilza ; Flores, Miryam Paola Alvarez ; Gomes, Renata Nascimento ; Souza, Marcelo Medina de ; Valerio, Hellen Paula ; Oliveira, Douglas Souza ; De Ocesano-Pereira, Carlos ; Botosso, Viviane Fongaro ; Jorge, Soraia Attie Calil ; Schattner, Mirta; Gomez, Ricardo M.; Chudzinski-Tavassi, Ana Marisa
Int J Mol Sci 2022 Sept; 23(18):10452

Proteomic profiling of the proteolytic events in the secretome of the transformed phenotype of melanocyte-derived cells using terminal amine isotopic labeling of substrates [2019]

Liberato, Tarcísio; Fukushima, Isabella; Kitano, Eduardo Shigueo ; Serrano, Solange Maria de Toledo ; Chammas, Roger; Zelanis, André
J Proteomics 2019 Feb;192:291-298

Pycard and BC017158 candidate genes of irm1 locus modulate inflammasome activation for IL-1β production [2022]

Borrego, Andrea ; Colombo, Francesca; Souza, Jean Gabriel de; Jensen, José Ricardo ; Ribeiro, Orlando Garcia ; Cabrera, Wafa Hanna Koury ; Starobinas, Nancy ; Magalhães, Geraldo Santana ; Eto, Silas Fernandes ; De Ocesano-Pereira, Carlos ; Goldfeder, Mauricio Barbugiani ; Pasqualoto, Kerly Fernanda Mesquita ; Ibañez, Olga Célia Martinez
Front Immunol 2022 June;13:899569