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(MRC) Medical Research Council

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Results 1-10 of 10

Evaluation of polymer choice on immunogenicity of chitosan coated PLGA NPs with surface-adsorbed pneumococcal protein antigen PspA4Pro [2021]

Kaneko, Kan; Miyaji, Eliane Namie ; Gonçalves, Viviane Maimoni ; Ferreira, Daniela M.; Solórzano, Carla; MacLoughlin, Ronan; Saleem, Imran
Int J Pharm 2021 Apr;599:120407

Expanding the toolbox for Trypanosoma cruzi: a parasite line incorporating a bioluminescence-fluorescence dual reporter and streamlined CRISPR/Cas9 functionality for rapid in vivo localisation and phenotyping [2018]

Costa, Fernanda Cristina; Francisco, Amanda Fortes; Jayawardhana, Shiromani; Calderano, Simone Guedes ; Lewis, Michael D.; Olmo, Francisco; Beneke, Tom; Gluenz, Eva; Sunter, Jack; Dean, Samuel; Kelly, John Morrison; Taylor, Martin Craig
PLoS Negl Trop Dis 2018 Apr;12(4):e0006388

Experimental human challenge defines distinct pneumococcal kinetic profiles and mucosal responses between colonized and non-colonized adults [2021]

Nikolaou, Elissavet; Jochems, Simon P.; Mitsi, Elena; Schanoski, Alessandra Soares
mBio 2021 Jan;12(1):e02020-20

Innate and adaptive nasal mucosal immune responses following experimental human pneumococcal colonization [2019]

Jochems, Simon P.; Ruiter, Karin de; Solórzano, Carla; Voskamp, Astrid; Mitsi, Elena; Nikolaou, Elissavet; Carniel, Beatriz F.; Pojar, Sherin; German, Esther L.; Reiné, Jesús; Schanoski, Alessandra Soares ; Hill, Helen; Robinson, Rachel; Hyder-Wright, Angela D.; Weight, Caroline M.; Durrenberger, Pascal F.; Heyderman, Robert S.; Gordon, Stephen B.; Smits, Hermelijn H.; Urban, Britta C.; Rylance, Jamie; Collins, Andrea M.; Wilkie, Mark D.; Lazarova, Lepa; Leong, Samuel C.; Yazdanbakhsh, Maria; Ferreira, Daniela M.
J clin invest 2019 Jul;129(10):4523-4538

Liposome-based dry powder vaccine immunization targeting the lungs induces broad protection against pneumococcus [2024]

Rodrigues, T. C.; Figueiredo, D. B.; Gonçalves, Viviane Maimoni ; Kaneko, K.; Saleem, I. Y.; Miyaji, Eliane Namie
J Control Release 2024 Apr; 368:184-198

Nasal pneumococcal density is associated with microaspiration and heightened human alveolar macrophage responsiveness to bacterial pathogens [2020]

Mitsi, Elena; Carniel, Beatriz; Reiné, Jesús; Rylance, Jamie; Zaidi, Seher; Schanoski, Alessandra Soares ; Connor, Victoria; Collins, Andrea M.; Schlitzer, Andreas; Nikolaou, Elissavet; Solórzano, Carla; Pojar, Sherin; Hill, Helen; Hyder-Wright, Angela D.; Jambo, Kondwani C.; Oggioni, Marco R.; Croix, Megan De Ste; Gordon, Stephen B.; Jochems, Simon P.; Ferreira, Daniela M.
Am J Respir Crit Care Med 2020 Feb;201(3)

Pneumococcal surface protein a-hybrid nanoparticles protect mice from lethal challenge after mucosal immunization targeting the lungs [2022]

Figueiredo, Douglas Borges de; Kaneko, Kan; Rodrigues, Tasson da Costa; MacLoughlin, Ronan; Miyaji, Eliane Namie ; Saleem, Imran; Gonçalves, Viviane Maimoni
Pharmaceutics 2022 June;14(6):1238

Serum levels of anti-PspA and anti-PspC IgG decrease with age and do not correlate with susceptibility to experimental human pneumococcal colonization [2021]

Araujo, Adriano Palharini de; Colichio, Gabriela Borges Cherulli ; Oliveira, Maria Leonor Sarno de ; German, Esther; Nikolaou, Elissavet; Chen, Tao; Adler, Hugh; Ferreira, Daniela M.; Miyaji, Eliane Namie
PloS One 2021 Fev;16(2)e0246540

Spatiotemporal bayesian modelling of scorpionism and its risk factors in the state of São Paulo, Brazil [2023]

Chiaravalloti-Neto, Francisco; Lorenz, Camila; Lacerda, Alec Brian; de Azevedo, Thiago Salomão; Candido, Denise Maria ; Eloy, Luciano José; Fan, Hui Wen ; Blangiardo, Marta; Pirani, Monica
PLoS Negl Trop Dis 2023 Jun; 17(6):e0011435

When could human challenge trials be deployed to combat emerging infectious diseases? Lessons from the case of a Zika virus human challenge trial [2019]

Palacios, Ricardo ; Shah, Seema K.
Trials 2019 Dec;20(suppl. 2):702