Advances in carbon nanotubes for malignant melanoma: a chance for treatment

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dc.contributorLaboratório de Biologia Molecularpt_BR
dc.contributor.authorLima, Elidamar Nunes de Carvalhopt_BR
dc.contributor.authorPiqueira, José Roberto Castilhopt_BR
dc.contributor.authorMaria, Durvanei Augustopt_BR
dc.identifier.citationLima ENC, Piqueira JRC, Maria DA. Advances in carbon nanotubes for malignant melanoma: a chance for treatment. Mol. Diagn. Ther.. 2018 Dec;22(6):703–15. doi:10.1007/s40291-018-0363-7.pt_BR
dc.description.abstractMalignant melanoma is an aggressive skin cancer with limited therapeutic options. Cancer is the second largest cause of death in society and one of the most difficult diseases to treat. Advances in biotechnology have enabled the current use of nanotechnology via the application of nanomaterials, especially as drug delivery systems for the transportation of very small particles. In this context, carbon nanotubes, with a potential role in the diagnosis and treatment of melanoma, are still an emerging research field. Their properties have been extensively studied for the use of antineoplastics drugs, as well as for DNA and RNA interference for the treatment of cancer. However, the most important challenge in nanomedicine is to decrease the toxicity and increase the biocompatibility of the nanomaterials used to transport therapeutic molecules. In this sense, this article addresses the recent advances in the use of carbon nanotubes in melanoma therapy and highlights the opportunities and challenges in this area. The advances and challenges involving these topics are essential to the success of nanoconjugate systems, and studies improving the comprehension of these nanosystems contribute to the development of specific antitumor therapies.pt_BR
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)pt_BR
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)pt_BR
dc.format.extentp. 703-715pt_BR
dc.publisherADIS Int Ltdpt_BR
dc.relation.ispartofMolecular Diagnosis & Therapypt_BR
dc.titleAdvances in carbon nanotubes for malignant melanomapt_BR
dc.contributor.externalUniversidade de São Paulo (USP)¦¦Brasilpt_BR
dc.title.suba chance for treatmentpt_BR
dc.relation.ispartofabbreviatedMol. Diagn. Ther.pt_BR
dc.identifier.citationabntv. 22, n. 6, p. 703–715, dez. 2018pt_BR
dc.identifier.citationvancouver2018 Dec;22(6):703–15pt_BR
dc.publisher.countryNew Zealandpt_BR
dc.contributor.butantanMaria, Durvanei Augusto|:Pesquisador|:Laboratório de Biologia Molecular|:pt_BR
dc.sponsorship.butantanConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)¦¦306124/2015-7pt_BR
dc.sponsorship.butantanConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)¦¦311613/2013-6pt_BR
dc.sponsorship.butantanCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)¦¦pt_BR
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