ZikaPLAN: addressing the knowledge gaps and working towards a research preparedness network in the Americas
Umea University¦¦Suécia ; The London School of Hygiene & Tropical Medicine (LSHTM)¦¦Reino Unido ; Universidade Federal de Pernambuco (UFPE)¦¦Brasil ; Universidade de Pernambuco (UPE)¦¦Brasil ; Centro de Pesquisas Aggeu Magalhães (CPqAM)¦¦Brasil ; Fundação Oswaldo Cruz (Fiocruz)¦¦Brasil ; Universidade Federal de Goiás (UFG)¦¦Brasil ; University of Liverpool¦¦Inglaterra ; Erasmus University Medical Center¦¦Holanda ; Johns Hopkins University (JHU)¦¦Estados Unidos ; Universidad del Valle¦¦Colômbia ; Instituto Oswaldo Cruz (IOC)¦¦Brasil ; Rega Institute of Medical Research¦¦Bélgica ; Institute of Tropical Medicine Antwerp¦¦Bélgica ; University of Glasgow¦¦Escócia ; Instituto De Medicina Tropical Pedro Kourí¦¦Cuba ; University of North Carolina at Chapel Hill (UNC)¦¦Estados Unidos ; Universidad Del Norte¦¦Colômbia ; La Jolla Institute for Immunology¦¦Estados Unidos ; University of California, San Diego¦¦Estados Unidos ; Institut Pasteur (IP)¦¦França ; Ulster University¦¦Reino Unido ; University of London¦¦Inglaterra ; Universidade Federal do Rio de Janeiro (UFRJ)¦¦Brasil ; Hospital Federal dos Servidores do Estado¦¦Brasil ; Hospital da Restauração¦¦Brasil ; Universidade de São Paulo (USP)¦¦Brasil ; University of Oxford¦¦Inglaterra
Appears in Collections:
Zika Preparedness Latin American Network (ZikaPLAN) is a research consortium funded by the European Commission to address the research gaps in combating Zika and to establish a sustainable network with research capacity building in the Americas. Here we present a report on ZikaPLAN's mid-term achievements since its initiation in October 2016 to June 2019, illustrating the research objectives of the 15 work packages ranging from virology, diagnostics, entomology and vector control, modelling to clinical cohort studies in pregnant women and neonates, as well as studies on the neurological complications of Zika infections in adolescents and adults. For example, the Neuroviruses Emerging in the Americas Study (NEAS) has set up more than 10 clinical sites in Colombia. Through the Butantan Phase 3 dengue vaccine trial, we have access to samples of 17,000 subjects in 14 different geographic locations in Brazil. To address the lack of access to clinical samples for diagnostic evaluation, ZikaPLAN set up a network of quality sites with access to well-characterized clinical specimens and capacity for independent evaluations. The International Committee for Congenital Anomaly Surveillance Tools was formed with global representation from regional networks conducting birth defects surveillance. We have collated a comprehensive inventory of resources and tools for birth defects surveillance, and developed an App for low resource regions facilitating the coding and description of all major externally visible congenital anomalies including congenital Zika syndrome. Research Capacity Network (REDe) is a shared and open resource centre where researchers and health workers can access tools, resources and support, enabling better and more research in the region. Addressing the gap in research capacity in LMICs is pivotal in ensuring broad-based systems to be prepared for the next outbreak. Our shared and open research space through REDe will be used to maximize the transfer of research into practice by summarizing the research output and by hosting the tools, resources, guidance and recommendations generated by these studies. Leveraging on the research from this consortium, we are working towards a research preparedness network.
Wilder-Smith A, Preet R, Brickley EB, Ximenes RA, Miranda-Filho D, Martelli CMT, et al. ZikaPLAN: addressing the knowledge gaps and working towards a research preparedness network in the Americas. Global health action. 2019 Oct;12(1):1666566. doi:10.1080/16549716.2019.1666566.
Link to cite this reference
The access to the publications deposited in this repository respects the licenses from journals and publishers.