Carbonylative negishi-type coupling of 2-Iodoglycals with alkyl and aryl halides
Appears in Collections:
C-Glycosides are valuable organic compounds in the field of medicinal chemistry due to their ubiquity inside living systems and pronounced biological activity. Herein, we describe an approach to alkyl-ketones bearing glycal units via the Pd-catalyzed carbonylative coupling of 2-iodoglycals and alkyl and aryl halides. Examples bearing a variety of functional groups are presented as well as a mechanistic proposal for this transformation.
Esteves HA., Darbem MP., Pimenta DC, Stefani HA.. Carbonylative negishi-type coupling of 2-Iodoglycals with alkyl and aryl halides. European J. Org. Chem.. 2019 Nov;2019(44):7384-7388. doi:10.1002/ejoc.201901081.
Link to cite this reference
The access to the publications deposited in this repository respects the licenses from journals and publishers.