Caracterización molecular de la nucleoproteína del virus de la rabia en canes procedentes de Arequipa, Perú

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dc.contributorLab. Bacteriologiapt_BR
dc.contributor.authorTorpoco, Carina Rosario Mantaript_BR
dc.contributor.authorHuallpa, Alfredo Miguel Berrocalpt_BR
dc.contributor.authorEspinoza-Culupú, Abrahampt_BR
dc.contributor.authorLópez-Ingunza, Ricardo Luispt_BR
dc.date.accessioned2020-07-09T21:25:53Z-
dc.date.available2020-07-09T21:25:53Z-
dc.date.issued2019pt_BR
dc.identifier.citationTorpoco CRM, Huallpa AMB, Espinoza-Culupú AO, López-Ingunza RL. Caracterización molecular de la nucleoproteína del virus de la rabia en canes procedentes de Arequipa, Perú. Rev. Peruana med. exp. salud publica. 2019 Mar;36(1):46-53. doi:10.17843/rpmesp.2019.361.3938.pt_BR
dc.identifier.urihttps://repositorio.butantan.gov.br/handle/butantan/2891-
dc.description.abstractObjective. To characterize the nucleoprotein (N) and establish the origin of the rabies virus in dogs coming from Arequipa. Materials and Methods. Thirty samples of nervous tissue from the departments of Arequipa and Puno were analyzed. Total RNA was extracted from the samples and cDNA was synthesized to amplify the nucleoprotein gene, sequence it, and perform bioinformatics analysis. Results. A defined group was formed with respect to the external group (European bat lyssavirus). This group was classified into two subgroups, one constituted by samples coming from Puno and Arequipa (subgroup A), and another one by samples from Puno (subgroup B), exhibiting a nucleotide identity of 99.9% in subgroup A. This group was classified in two subgroups, one constituted by samples coming from Puno and Arequipa (subgroup A), and another one by samples from Puno (subgroup B), observing a nucleotide identity of 99.9% in subgroup A. Conclusions. The groupings of viral sequences show that the cases of canine rabies reported in Arequipa are the result of the expansion of canine rabies from the endemic region of Puno.pt_BR
dc.format.extentp. 46-53pt_BR
dc.language.isoSpanishpt_BR
dc.relation.ispartofRevista Peruana de Medicina Experimental y Salud Públicapt_BR
dc.rightsOpen Accesspt_BR
dc.titleCaracterización molecular de la nucleoproteína del virus de la rabia en canes procedentes de Arequipa, Perúpt_BR
dc.typeArticlept_BR
dc.identifier.doi10.17843/rpmesp.2019.361.3938pt_BR
dc.identifier.urlhttp://dx.doi.org/10.17843/rpmesp.2019.361.3938pt_BR
dc.contributor.externalInstituto Nacional de Salud¦¦Perupt_BR
dc.contributor.externalUniversidad Nacional Mayor de San Marcos (UNMSM)¦¦Perupt_BR
dc.contributor.externalUniversidade de São Paulo (USP)¦¦Brasilpt_BR
dc.identifier.citationvolume36pt_BR
dc.identifier.citationissue1pt_BR
dc.subject.keywordVirus ARNpt_BR
dc.subject.keywordVirus de la Rabiapt_BR
dc.subject.keywordSecuenciación de Nucleótidos de Alto Rendimientopt_BR
dc.subject.keywordPerrospt_BR
dc.subject.keywordPerúpt_BR
dc.relation.ispartofabbreviatedRev Peruana med exp salud publicapt_BR
dc.identifier.citationabntv. 36, n. 1, p. 46-53, mar. 2019pt_BR
dc.identifier.citationvancouver2019 Mar;36(1):46-53pt_BR
dc.contributor.butantanEspinoza-Culupú, Abraham|:Aluno|:Lab. Bacteriologia|:pt_BR
dc.identifier.bvsccBR78.1pt_BR
dc.identifier.bvsdbIBProdpt_BR
dc.description.dbindexedYespt_BR
item.grantfulltextopen-
item.languageiso639-1Spanish-
item.openairetypeArticle-
item.fulltextCom Texto completo-
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