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Safety and immunogenicity of the tetravalent, live-attenuated dengue vaccine Butantan-DV in adults in Brazil: a two-step, double-blind, randomised placebo-controlled phase 2 trial

Author
Kallas, Esper Georges;  Precioso, Alexander Roberto ;  Palacios, Ricardo ;  Thomé, Beatriz;  Braga, Patrícia Emília ;  Vanni, Tazio ;  Campos, Lúcia M A;  Ferrari, Lilian;  Mondini, Gabriela ;  Salomão, Maria da Graça ;  Silva, Anderson da ;  Espinola, Heloisa Maxímo ;  Santos, Joane do Prado ;  Santos, Cecilia L S;  Timenetsky, Maria do Carmo S T;  Miraglia, João Luiz ;  Gallina, Neuza Maria Frazatti ;  Weiskopf, Daniela;  Sette , Alessandro;  Goulart, Raphaella;  Salles, Rafael Tavares;  Maestri, Alvino;  Sallum, Adriana Maluf Elias;  Farhat, Sylvia Costa Lima;  Sakita, Neusa Keico;  Ferreira, Juliana C O A;  Silveira, Cassia G T;  Costa, Priscilla R;  Raw, Isaias ;  Whitehead, Stephen S;  Durbin, Anna P.;  Kalil, Jorge
Butantan affiliation
Centro de Ensaios Clínicos e Farmacovigilância ;  Laboratório de Desenvolvimento de Vacinas 
External affiliation
Universidade de São Paulo (USP)¦¦Brasil ;  Instituto Adolfo Lutz (IAL)¦¦Brasil ;  La Jolla Institute for Immunology¦¦Estados Unidos ;  National Institutes of Health (NIH)¦¦Estados Unidos ;  Johns Hopkins Bloomberg School of Public Health¦¦Estados Unidos 
Publication type
Article
Language
English
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Reference
Kallas EG, Precioso AR, Palacios R, Thomé B, Braga PE, Vanni T, et al. Safety and immunogenicity of the tetravalent, live-attenuated dengue vaccine Butantan-DV in adults in Brazil: a two-step, double-blind, randomised placebo-controlled phase 2 trial. Lancet Infect. Dis.. 2020 Mar;20(7):839-850. doi:10.1016/S1473-3099(20)30023-2.
Link to cite this reference
https://repositorio.butantan.gov.br/handle/butantan/2991
Journal title
The Lancet Infectious Diseases 
Funding agency
National Institutes of Health (NIH) ;  Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) 
Issue Date
2020

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