A metal-free blue chromophore derived from plant pigments


Publication type
Article
Language
English
Access rights
Open Access
Appears in Collections:
Metrics
Abstract
Blue natural pigments are rare, especially among plants. However, flowering species that evolved to attract Hymenoptera pollinators are colored by blue anthocyanin-metal complexes. Plants lacking anthocyanins are pigmented by betalains but are unable to produce blue hues. By extending the p-system of betalains, we designed a photostable and metal-free blue dye named BeetBlue that did not show toxicity to human hepatic and retinal pigment epithelial cells and does not affect zebrafish embryonal development. This chiral dye can be conveniently synthesized from betalamic acid obtained from hydrolyzed red beetroot juice or by enzymatic oxidation of L-dopa. BeetBlue is blue in the solid form and in solution of acidified polar molecular solvents, including water. Its capacity to dye natural matrices makes BeetBlue the prototype of a new class of low-cost bioinspired chromophores suitable for a myriad of applications requiring a blue hue.
Reference
Freitas-Dörr B.C., Machado C.O., Pinheiro A.C., Fernandes A.B., Dörr F.A., Pinto E., et al. A metal-free blue chromophore derived from plant pigments. Sci. Adv.. 2020 Apr;6(14):eaaz0421. doi:10.1126/sciadv.aaz0421.
Link to cite this reference
https://repositorio.butantan.gov.br/handle/butantan/3010
Journal title
Issue Date
2020


Files in This Item:

10.1126sciadv.aaz0421.pdf
Size: 1.31 MB
Format: Adobe PDF
View/Open
Show full item record

The access to the publications deposited in this repository respects the licenses from journals and publishers.