COVID-19 in long-term care facilities in Brazil: serological survey in a post-outbreak setting

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dc.contributorCentro de Ensaios Clínicos e Farmacovigilânciapt_BR
dc.contributor.authorBarros, Eliana Nogueira Castro dept_BR
dc.contributor.authorValle, Adriana P. dopt_BR
dc.contributor.authorBraga, Patrícia Emíliapt_BR
dc.contributor.authorViscondi, Juliana Y. K.pt_BR
dc.contributor.authorFonseca, Antonio R. B. dapt_BR
dc.contributor.authorVanni, Taziopt_BR
dc.contributor.authorSilva, Anderson dapt_BR
dc.contributor.authorCardoso, Maria Reginapt_BR
dc.contributor.authorVillas-Boas, Paulo José F.pt_BR
dc.contributor.authorPrecioso, Alexander Robertopt_BR
dc.identifier.citationBarros ENC, Valle AP., Braga PE, Viscondi JY.K., Fonseca AR.B., Vanni T, et al. COVID-19 in long-term care facilities in Brazil: serological survey in a post-outbreak setting. Rev. Inst. Med. Trop. Sao Paulo. 2021 Jan;63:e10. doi:10.1590/S1678-9946202163010.pt_BR
dc.description.abstractThis cross-sectional seroepidemiological survey presents the seroprevalence of SARS-CoV-2 in a population living in 15 Long-Term Care Facilities (LTCFs), after two intra-institutional outbreaks of COVID-19 in the city of Botucatu, Sao Paulo State, Brazil. Residents were invited to participate in the serological survey performed in June and July 2020. Sociodemographic and clinical characterization of the participants as well as the LTCF profile were recorded. Blood samples were collected, processed and serum samples were tested using the rapid One Step COVID-19 immunochromatography test to detect IgM and IgG anti-SARS-CoV-2. Among 209 residents, the median of age was 81 years old, 135 (64.6%) were female and 171 (81.8%) self-referred as being white. An overall seroprevalence of 11.5% (95% CI: 7.5% – 16.6%) was found. The highest seroprevalences of 100% and 76.9% were observed in LTCFs that had experienced COVID-19 outbreaks. Most residents with positive immunochromatography tests (70.8%) referred previous contact with a confirmed COVID-19 case. Although there was a relatively low seroprevalence of COVID-19 in the total number of elderly people, this population is highly vulnerable and LTCFs are environments at higher risk for COVID-19 dissemination. A well-established test for COVID-19 policies, the adequate characterization of the level of interaction between residents and the healthcare provider team and the level of complexity of care are crucial to monitor and control the transmission of SARS-CoV-2 in these institutions.pt_BR
dc.relation.ispartofRevista do Instituto de Medicina Tropical de São Paulopt_BR
dc.rightsOpen accesspt_BR
dc.titleCOVID-19 in long-term care facilities in Brazil: serological survey in a post-outbreak settingpt_BR
dc.rights.licenseCC BY-NCpt_BR
dc.contributor.external(UNESP) Universidade Estadual Paulista Júlio de Mesquita Filhopt_BR
dc.contributor.external(USP) Universidade de São Paulopt_BR
dc.subject.keywordlong-term care facilitypt_BR
dc.relation.ispartofabbreviatedRev Inst Med Trop Sao Paulopt_BR
dc.identifier.citationabntv. 63, e10, jan. 2021pt_BR
dc.identifier.citationvancouver2021 Jan;63:e10pt_BR
dc.contributor.butantanBarros, Eliana Nogueira Castro de|:Colaboador|:Laboratório de Farmacoepidemiologia|:PrimeiroAutor|:Autor de correspondênciapt_BR
dc.contributor.butantanBraga, Patrícia Emília|:Pesquisador|:Centro de Ensaios Clínicos e Farmacovigilânciapt_BR
dc.contributor.butantanViscondi, Juliana Y. K.|:Outros|:Centro de Ensaios Clínicos e Farmacovigilânciapt_BR
dc.contributor.butantanVanni, Tazio|:Pesquisador|:Centro de Ensaios Clínicos e Farmacovigilânciapt_BR
dc.contributor.butantanSilva, Anderson da|:Outros|:Centro de Ensaios Clínicos e Farmacovigilânciapt_BR
dc.contributor.butantanPrecioso, Alexander Roberto|:Pesquisador|:Centro de Ensaios Clínicos e Farmacovigilânciapt_BR
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