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Restoring endoplasmic reticulum proteostasis to treat neurological disorders

Author
Medinas, Danilo Bilches;  Arshad, Najla;  Parakh, Sonam;  Miyamoto, Sayuri;  Zambelli, Vanessa Olzon 
Butantan affiliation
(LEDS) Lab. Dor e Sinalização 
External affiliation
(USP) Universidade de São Paulo ;  Universidad de Chile ;  Centro de Gerociência, Saúde do Cérebro e Metabolismo ;  Yale University ;  Macquarie University 
Publication type
Article
Language
English
Access rights
Open access
Terms of use
CC BY
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Reference
Medinas DB, Arshad N, Parakh S, Miyamoto S, Zambelli VO. Restoring endoplasmic reticulum proteostasis to treat neurological disorders. Front Pharmacol. 2023 Mar; 14:1176805. doi:10.3389/fphar.2023.1176805.
Link to cite this reference
https://repositorio.butantan.gov.br/handle/butantan/4850
Journal title
Frontiers in Pharmacology 
Keywords
neurological disorders;  ischemia-reperfusion injury;  spinal cord injury;  endoplasmic reticulum;  proteostasis;  unfolded protein response;  small molecules;  drug discovery
Funding agency
(FONDECYT) Fondo Nacional de Desarrollo Científico y Tecnológico ;  (FAPESP) Fundação de Amparo à Pesquisa do Estado de São Paulo ;  (MNDRA) MND Research Australia ;  (DARF) The Dementia Australia Research Foundation ;  (NDR) Neurodegenerative Disease Research Inc ;  (CNPq) Conselho Nacional de Desenvolvimento Científico e Tecnológico 
Issue Date
2023

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