Enriquecimento ambiental com aveia em camundongos Swiss

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Today we can say that it is almost impossible to think of research without animal models, and the most iconic model used since the mid-17th century is the House Mouse (Mus musculus), whose ancestor originated in Central Asia. (ANDRADE, 2002; KO and LUCA, 2009). The experiment was carried out with animals with stereotyped behaviors characteristic of stress such as aggressiveness, repetitive movements and gnawing the bars, the animals were organized into 4 groups, each of which had 3 subgroups, of which each group was offered environmental enrichments of the type foodstuffs, made with an oat- based mixture in two textures. The evaluation was carried out during 45 days, in 6 weighings, the data obtained were analyzed in the GraphPad Prism 9 program, which allows the statistical and variance evaluation, in addition to the construction of graphs. We concluded that despite the enrichments being different from each other, there was no significant change in weight gain between them, but there were distinct behavioral changes between each group and each subgroup.
Abstract in Portuguese
Hoje podemos dizer que é quase impossível pensar em pesquisa sem modelos animais, e o modelo mais icônico utilizado desde meados do século XVIII é o Camundongo Doméstico (Mus musculus), tem como antepassado com origem na Ásia central.(ANDRADE, 2002; KO e LUCA, 2009) O experimento foi realizado com animais com comportamentos estereotipados característicos do estresse como agressividade, movimentos repetitivos e roer as grades, os animais foram organizados em 4 grupos, destes, cada um possuía 3 subgrupos, dos quais, foi ofertado a cada grupo enriquecimentos ambientais do tipo alimentar, feitos com mistura a base de aveia em duas texturas. A avaliação foi feita durante 45 dias, em 6 pesagens, os dados obtidos foram analisados no programa GraphPad Prism 9, que possibilita a avaliação estatística e de variância, além da construção de gráficos. Concluímos que apesar dos enriquecimentos serem distintos entre si não ocorreu mudança significativa no ganho de peso entre eles, mas sim ocorreu mudanças comportamentais distintas entre cada grupo e cada subgrupo.
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