(LDV) Lab. Desenvolvimento de Vacinas

Publicações
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Resultados 41-60 de 149

Fusion of PspA to detoxified pneumolysin enhances pneumococcal vaccine coverage [2023]

Milani, Barbara; Santos, Tanila Wood dos Santos; Guerra, Maria Eduarda Souza; Oliveira, Sheila; Goulart, Cibelly; André, Greiciely O.; Leite, Luciana Cezar de Cerqueira ; Converso, Thiago R.; Darrieux, Michelle
PloS One 2023 Dec; 18(12):e0291203

A fusion protein comprising pneumococcal surface protein A and a pneumolysin derivate confers protection in a murine model of pneumococcal pneumonia [2022]

Santos, Tanila Wood dos; Gonçalves, Pedro Almeida; Rodríguez, Dunia ; Pereira, José Aires; Martinez, Carlos Augusto Real; Leite, Luciana Cezar de Cerqueira ; Ferraz, Lucio F. C.; Converso, Thiago Rojas; Darrieux, Michelle
PloS One 2022 Dec; 17(12):e0277304

Gene silencing based on RNA-guided catalytically inactive Cas9 (dCas9): a new tool for genetic engineering in Leptospira [2019]

Fernandes, Luis Guilherme Vírgílio ; Guaman, L. P.; Vasconcellos, S. A.; Heinemann, Marcos B.; Picardeau, M.; Nascimento, Ana Lúcia Tabet Oller do
Sci Rep 2019 Feb;9:1839

Genetic manipulation of pathogenic Leptospira: CRISPR interference (CRISPRi)-mediated gene silencing and rapid mutant recovery at 37 °C [2021]

Fernandes, Luis Guilherme Vírgílio ; Hornsby, R. L.; Nascimento, Ana Lúcia Tabet Oller do ; Nally, J. E.
Sci Rep 2021 Jan;11:1768

A global perspective on vaccines: priorities, challenges and online information [2019]

Tagliabue, Aldo; Leite, Luciana Cezar de Cerqueira ; Leroy, Odile Y; Rappuoli, Rino
Front Immunol 2019 Nov;10(2556)

Global proteome of the saprophytic strain Leptospira biflexa and comparative analysis with pathogenic strain Leptospira interrogans uncover new pathogenesis mechanisms [2024]

Filho, Edson G. Nascimento; Vieira, Mônica L.; Dias, Meriellen; Mendes, Maria A.; Sanchez, Fabio B.; Setubal, João C.; Heinemann, Marcos B.; Souza, Gisele O.; Pimenta, Daniel Carvalho ; Nascimento, Ana Lúcia Tabet Oller
J Proteomics 2024 Apr; 297:105125

Gold nanoparticles modulate BCG-induced innate immune memory in human monocytes by shifting the memory response towards tolerance [2020]

Swartzwelter, Benjamin J.; Barbero, Francesco; Verde, Alessandro; Mangini, Maria; Pirozzi, Marinella; Luca, Anna Chiara De; Puntes, Victor F.; Leite, Luciana Cezar de Cerqueira ; Italiani, Paola; Boraschi, Diana
Cells 2020 Jan;9(2):284

Heparin-binding protein release is strongly induced by Leptospira species and is a candidate for an early diagnostic marker of human Leptospirosis [2019]

Vieira, Mônica Larucci ; Persson, Sandra; Lopes-Ferreira, Monica ; Romero, Eliete C.; Kirchgatter, Karin; Nascimento, Ana Lúcia Tabet Oller do ; Herwald, Heiko
J infect dis 2019 Mar;219(6):996-1006

Heterologous expression of the pathogen-specific LIC11711 gene in the Saprophyte L. biflexa increases bacterial binding to laminin and plasminogen [2020]

Kochi, Leandro Toshio ; Fernandes, Luis Guilherme Vírgílio ; Nascimento, Ana Lúcia Tabet Oller do
Pathogens 2020 Jul;9(8):599

High stabilization and hyperactivation of a recombinant β-Xylosidase through immobilization strategies [2021]

Corradini, Felipe A.S.; Milessi, Thais S.; Gonçalves, Viviane Maimoni ; Ruller, Roberto; Sargo, Cíntia R.; Lopes, Laiane A.; Zangirolami, Teresa C.; Tardioli, Paulo W.; Giordano, Roberto C.; Giordano, Raquel L.C.
Enzyme Microb Technol 2021 Apr;145:109725

Host cell binding mediated by Leptospira interrogans adhesins [2022]

Takahashi, Maria Beatriz; Teixeira, Aline Rodrigues Florêncio ; Nascimento, Ana Lúcia Tabet Oller
Int J Mol Sci 2022 Oct-Dec; 23(24):15550

Identification of a novel protein in the genome sequences of Leptospira interrogans with the ability to interact with host's components [2020]

Rossini, Amanda Diaz ; Teixeira, Aline Rodrigues Florêncio ; Souza Filho, A.; Souza, G.O.; Vasconcellos, S.A.; Heinemann, M.B.; Romero, E.C.; Nascimento, Ana Lúcia Tabet Oller do
J Microbiol Immunol Infect 2020 Feb;53(1):163-175

Identification of leptospiral protein antigens recognized by WC1+ γδ T cell subsets as target for development of recombinant vaccines [2022]

Teixeira, Aline Rodrigues Florêncio ; Gillespie, Alexandria; Yirsaw, Alehegne; Britton, Emily; Telfer, Janice C.; Nascimento, Ana Lúcia Tabet Oller do ; Baldwin, Cynthia L.
Infect Immun 2022 Oct;90(1):e00492-21

Immune response induced in mice by a hybrid rPotD-PdT pneumococcal protein [2022]

Converso, Thiago Rojas; Goulart, Cibelly ; Rodríguez, Dunia ; Guerra, Maria Eduarda Souza; Leite, Luciana Cezar de Cerqueira
PloS One 2022 Aug; 17(8): e0273017

Immunization with PhtD truncated fragments reduces nasopharyngeal colonization by Streptococcus pneumoniae [2020]

Andre, Greiciely O.; Assoni, Lucas; Rodríguez, Dunia ; Leite, Luciana Cezar de Cerqueira ; Santos, Thaisy E.P. dos; Ferraz, Lucio F.C.; Converso, Thiago Rojas; Darrieux, Michelle
Vaccine 2020 Apr;38(26):4146-4153

Immunoprotective activity induced by leptospiral outer membrane proteins in hamster model of acute leptospirosis [2020]

Teixeira, Aline Rodrigues Florêncio ; Pereira, Maria Fernanda Cavenague ; Kochi, Leandro Toshio ; Fernandes, Luis Guilherme Vírgílio ; Souza, Gisele O; Souza Filho, Antonio Francisco de; Vasconcellos, Silvio A.; Heinemann, Marcos Bryan; Nascimento, Ana Lúcia Tabet Oller do
Front Immunol 2020 Oct;10:568694

Imunoterápico, composição farmacêutica e uso de imunoterápico para manufatura de medicamento para uso no tratamento de câncer [2009]

Leite, Luciana Cezar de Cerqueira ; Nascimento, Ivan Pereira ; Chade, Daher Cezar; Borra, Ricardo Carneiro; Villanova, Fabiola Elizabeth; Andrade, Enrico Ferreira Martins de; Leite, Katia Ramos Moreira; Srougi, Miguel; Raw, Isaias ; Priscila Maria de Andrade Borra
Patent Leite, Luciana Cezar de Cerqueira; Nascimento, Ivan Pereira; Chade, Daher Ceza; Borra, Ricardo Carneiro; Villanova, Fabiola Elizabeth; Andrade, Enrico Ferreira Martins de; Leite, Katia Ramos Moreira; Srougi, Miguel; Raw, Isaías; Borra, Priscila Maria de Andrade; Fundação Butantan;Hospital Alemão Oswaldo Cruz . Imunoterápico, composição farmacêutica e uso de imunoterápico para manufatura de medicamento para uso no tratamento de câncer. Patente. BR. PI0904468-0 A2. 07.10.2009

In silico analysis and functional characterization of a leucine-rich repeat protein of leptospira interrogans [2024]

Inácio, Joao Pedro Gaspar ; Takahashi, Maria Beatriz ; Teixeira, Aline Rodrigues Florêncio ; Nascimento, Ana Lúcia Tabet Oller
Int J Med Microbiol 2024 Sep; 316:151633

In silico analysis of genetic VapC profiles from the toxin-antitoxin type II VapBC modules among pathogenic, intermediate, and non-pathogenic Leptospira [2019]

Lopes, Alexandre Paulo Yague ; Azevedo, Bruna Oliveira Pigatto ; Emídio, Rebeca Cordellini ; Damiano, Deborah Kohn ; Nascimento, Ana Lúcia Tabet Oller do ; Barazzone, Giovana Cappio
Microorganisms 2019 Feb;7(2):56