Quantifying the affinity of trypanosoma cruzi RPA-1 to the single-stranded DNA overhang of the telomere using surface plasmon resonance
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Surface plasmon resonance (SPR) biosensors provide real-time binding affinity measurements between a pair of biomolecules, characterizing its interaction dynamics. An example of Trypanosoma cruzi’s RPA-1 and a single-stranded DNA telomere sequence is presented with detailed guidelines and fundamentals for SPR technology.
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