Proteomic dataset comparing strains of Leptospira borgpetersenii serovar Hardjo cultured at different temperatures
Autor
Afiliação Butantan
Afiliação externa
Tipo de documento
Article
Idioma
English
Direitos de acesso
Open access
Licença de uso
CC BY
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Resumo em inglês
Leptospirosis is a global zoonotic bacterial disease which is a threat for humans and most mammals. Bacterin vaccines for leptospirosis are available however they are severely limited in cross protection between serogroups. Leptospira typically colonize the kidneys of reservoir hosts where they are subsequently shed in the urine and persist in the environment and can thus be indirectly or directly transmitted to incidental hosts. Leptospira borgpetersenii serovar Hardjo is the primary cause of leptospirosis in cattle which can result in abortion, unhealthy calves, and rebreed problems. This dataset comprises proteomic profiles of four strains of L. borgpetersenii serovar Hardjo propagated at the routinely utilized culture temperature of 29 °C, and a newly achieved culture temperature of 37 °C, which more closely emulates the temperature of an infected host. The strains analyzed include JB197 (established strain that causes Hardjo atypical acute disease in the hamster model of leptospirosis), HB203 (established strain, causes typical chronic disease in hamsters), as well as TC129 and TC273 (recently isolated strains from the central United States). Differential expression profiles were detected not only between strains but also within strains between culture temperatures. Mass spectrometry data are available via ProteomeXchange with identifier PXD032831.
Referência
Putz EJ., Fernandes LGV, Bayles DO., Lippolis JD., Nally JE.. Proteomic dataset comparing strains of Leptospira borgpetersenii serovar Hardjo cultured at different temperatures. Data Brief. 2022 Dec; 45:108713. doi:10.1016/j.dib.2022.108713.
URL permanente para citação desta referência
https://repositorio.butantan.gov.br/handle/butantan/4731
URL
https://doi.org/10.1016/j.dib.2022.108713
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Data de publicação
2022
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Este item está licenciada sob uma Licença Creative Commons